Evidence map›Paper›PMID 40879817›Full record

SynthesisHernia : the journal of hernias and abdominal wall surgery2025

Subcutaneous versus retromuscular approach for the minimally invasive surgical treatment of rectus diastasis with concomitant ventral hernia: systematic review and meta-analysis of current techniques.

Lidia Castagneto-Gissey, Maria Francesca Russo, Piergaspare Palumbo, James Casella-Mariolo, Vito D'Andrea, Maria Irene Bellini, Giulio Illuminati, Giovanni Casella

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Hernia : the journal of hernias and abdominal wall surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lidia Castagneto-GisseyDepartment of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy. lidia.castagnetogissey@uniroma1.it.ORCID 0000-0002-3800-167X
Maria Francesca RussoDepartment of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy.
Piergaspare PalumboDepartment of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy.
James Casella-MarioloDepartment of General and Emergency Surgery, Ospedale dei Castelli (NOC), ASL Roma 6, Rome, Italy.
Vito D'AndreaDepartment of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy.
Maria Irene BelliniDepartment of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy.
Giulio IlluminatiDepartment of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy.
Giovanni CasellaDepartment of Surgery, Sapienza University of Rome, Viale Regina Elena, 324, Rome, 00161, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis systematic review and meta-analysis aims to evaluate the outcomes of laparoendoscopic extraperitoneal techniques for repairing rectus diastasis (RD) with concomitant ventral hernias, focusing on recurrence rates, surgical site occurrences, and the effectiveness of various surgical approaches and mesh placement sites.

methodsA comprehensive literature search was conducted using PubMed and the Cochrane Library, adhering to PRISMA guidelines. Prospective and retrospective cohort studies involving adults with RD and concomitant ventral hernias were included. Surgical techniques were classified based on working space (subcutaneous vs. retromuscular) and wall repair technique (stapled vs. fascial plication suture). The primary outcome was recurrence of RD or hernia, and secondary outcomes included seroma, surgical site infections (SSIs), and bleeding.

resultsTwenty-two studies comprising 1,616 patients were analyzed. Mean age was 45.6 years, BMI 30.5 kg/m², with a mean follow-up of 10.5 months. All studies were non-randomized and rated as having a “Serious” risk of bias using the ROBINS-I tool. Recurrence occurred in 19 patients (0.99%), with no significant differences between subcutaneous and retromuscular approaches (0.93% vs. 1.16%, p = 0.802) or between stapled and fascial plication techniques (0% vs. 1.18%, p = 0.090). Seroma rates were significantly higher in the subcutaneous group compared to retromuscular approach (11.8% vs. 0.70%, p < 0.001). SSIs were more common in subcutaneous approaches (2.33% vs. 0.58%, 0.005). Bleeding was low across all groups (1.3%), with higher rates in the stapled compared to the fascial plication group (6.39% vs. 0.37%, p < 0.001).

conclusionsLaparoendoscopic extraperitoneal approaches for RD and ventral hernia repair demonstrate favorable outcomes, with low and comparable recurrence rates among subgroups. The subcutaneous approach is associated with a higher risk of seroma formation while the stapled technique may increase bleeding risk. Further studies with higher methodological quality are needed to guide optimal technique selection.

Indexed as

Diastasis, MuscleHernia, VentralHerniorrhaphyLaparoscopyRectus AbdominisFasciotomyHumansRecurrenceSeromaSurgical MeshSurgical Wound InfectionSuture TechniquesHernia repairRectus diastasisRecurrenceSeromaUmbilical herniaVentral hernia

Identifiers

PMID40879817
PMCPMC12397138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.