Evidence map›Paper›PMID 40879778›Full record

SynthesisSurgical endoscopy2025

Learning curve of minimally invasive complete mesocolic excision for right-sided colon cancer: a systematic review.

Cristián Jarry, Christophe Riquoir, Javier Vela, Felipe Bellolio, Satish Warrier, Alexander Heriot, José Tomás Larach

Abstract readSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cristián Jarry *Colorectal Surgery Unit, Department of Digestive Surgery, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 4th Floor, 8330077, Santiago, Chile.ORCID http://orcid.org/0000-0003-3548-4909
Christophe Riquoir *Surgery Service, Hospital Santiago Oriente, Dr. Luis Tisné B. Peñalolén, Santiago, Chile.ORCID http://orcid.org/0000-0001-7462-2708
Javier VelaColorectal Surgery Unit, Department of Digestive Surgery, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 4th Floor, 8330077, Santiago, Chile.ORCID http://orcid.org/0000-0002-0624-0940
Felipe BellolioColorectal Surgery Unit, Department of Digestive Surgery, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 4th Floor, 8330077, Santiago, Chile.ORCID http://orcid.org/0000-0003-3289-9498
Satish WarrierPeter MacCallum Cancer Centre, Melbourne, Australia.ORCID http://orcid.org/0000-0003-0146-1485
Alexander HeriotPeter MacCallum Cancer Centre, Melbourne, Australia.ORCID http://orcid.org/0000-0001-9846-8776
José Tomás LarachColorectal Surgery Unit, Department of Digestive Surgery, Pontificia Universidad Católica de Chile, Diagonal Paraguay 362, 4th Floor, 8330077, Santiago, Chile. jtlarach@uc.cl.ORCID http://orcid.org/0000-0001-5242-9456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundComplete mesocolic excision (CME) for right-sided colon cancer offers oncological advantages but remains technically demanding, which limits its widespread adoption. Understanding the learning curve (LC) for this complex procedure is essential to ensure safe implementation and to guide structured surgical training. This systematic review aims to evaluate the learning curve of minimally invasive CME for right-sided colon cancer, focusing on operative metrics and complications, and estimating the number of cases required to achieve proficiency.

methodsThis systematic review adhered to PRISMA 2020 guidelines and was registered in PROSPERO (CRD42024615748). A comprehensive search across six databases included studies utilizing CUSUM analysis to evaluate the LC of minimally invasive CME. Outcomes of interest included operative time, complications, pathological quality, and oncological metrics. Studies with fewer than ten cases or lacking LC focus were excluded. Risk of bias was assessed using the ROBINS-I framework.

resultsSeven studies were included, comprising laparoscopic and robotic CME. Proficiency thresholds ranged from 21 to 32 cases, with consistent reductions in operative time across studies. Complication rates varied (3.6-13%) but remained within acceptable limits in most series. Lymph node harvest was adequate even during early phases, with minor variations between studies. Heterogeneity in study design and reporting limited meta-analysis but highlighted the utility of standardized CUSUM analysis for evaluating LCs.

conclusionsThis review establishes a consistent proficiency plateau for minimally invasive CME at 21-32 cases, supporting its safety and efficacy even during initial phases. However, methodological variability and lack of standardized reporting underscore the need for further research and validated training programs to optimize outcomes and ensure broader adoption.

Indexed as

ColectomyColonic NeoplasmsLaparoscopyLearning CurveMesocolonRobotic Surgical ProceduresClinical CompetenceHumansOperative TimePostoperative ComplicationsColorectal cancerColorectal surgeryComplete mesocolic excisionLearning curveMinimally invasive surgery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.