Evidence map›Paper›PMID 40879701›Full record

ArticleJournal of microscopy2026

Exploring collagen fibrillogenesis at the nanoscale: Tip-enhanced Raman imaging of protofibrils.

Maria A Paularie, Emerson A Fonseca, Vitor Monken, André G Pereira, Rafael P Vieira, Ado Jorio

Abstract read
In one paragraph

Article in Journal of microscopy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maria A PaularieDepartamento de Física, Instituto de Ciências Exatas (ICEx), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brasil.
Emerson A FonsecaDepartamento de Física, Instituto de Ciências Exatas (ICEx), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brasil.
Vitor MonkenPrograma de Pós Graduação em Inovação Tecnológica, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brasil.
André G PereiraDepartamento de Física, Instituto de Ciências Exatas (ICEx), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brasil.
Rafael P VieiraPrograma de Pós Graduação em Inovação Tecnológica, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brasil.ORCID 0000-0003-3176-1681
Ado JorioDepartamento de Física, Instituto de Ciências Exatas (ICEx), Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, Brasil.ORCID 0000-0002-5978-2735

Funding

Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-01860-22Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-04852-23Fundação de Amparo à Pesquisa do Estado de Minas Gerais RED-00081-23
6 · The paper itself

Abstract

Collagen, a key structural component of the extracellular matrix, assembles through a hierarchical process of fibrillogenesis. Despite extensive studies on mature collagen fibrils, intermediates such as protofibrils remain underexplored, particularly at the nanoscale. This study presents hyperspectral tip-enhanced Raman spectroscopy (TERS) imaging of collagen protofibrils, offering chemical and structural insights into early fibrillogenesis by acquiring nanoscale molecular profiles of collagen intermediates. TERS spectra, complemented by atomic force microscopy (AFM) images, reveal characteristic molecular vibrational modes, including the phenylalanine ring breathing mode, amide II and

Indexed as

CollagenSpectrum Analysis, RamanAnimalsExtracellular MatrixMicroscopy, Atomic ForceCollagencollagen protofibrilsfibrillogenesisfingerprintTERS

Identifiers

PMID40879701
PMCPMC12746377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.