Evidence map›Paper›PMID 40879668›Full record

ArticleMicrobiology spectrum2025

Biofilm development in three-dimensional models infected with

Matheus Bordoy Mendonça, Ana Karla Lima Freire Cabral, Bruno Bulgarelli Adorno Arantes, Rafaela Cristine Dos Santos, Kaila Petronila Medina-Alarcón, Kelvin Sousa Dos Santos, Marcos William De Lima Gualque, Lígia de Souza Fernandes, Jenyffie Araujo Belizario, Thais Yume Toriy Fuzinaga and 7 more

Abstract read
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Dermatophytosis: An Update on Global Epidemiology.Journal of fungi (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Matheus Bordoy MendonçaDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.ORCID 0000-0001-8751-460X
Ana Karla Lima Freire CabralDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Bruno Bulgarelli Adorno ArantesDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Rafaela Cristine Dos SantosDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Kaila Petronila Medina-AlarcónDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Kelvin Sousa Dos SantosDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Marcos William De Lima GualqueDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Lígia de Souza FernandesDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Jenyffie Araujo BelizarioDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Thais Yume Toriy FuzinagaDepartment of Pharmaceutical Sciences, University of Sao Paulo, Ribeirao Preto, Brazil.
Camila Martins KawakamiDepartment of Pharmaceutical Sciences, University of Sao Paulo, Ribeirao Preto, Brazil.
Ana Julia Pasuch GluzezakDepartment of Pharmaceutical Sciences, University of Sao Paulo, Ribeirao Preto, Brazil.
Luis R MartinezDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, Florida, USA.ORCID 0000-0001-6372-6501
Lorena Rigo Gaspar CordeiroDepartment of Pharmaceutical Sciences, University of Sao Paulo, Ribeirao Preto, Brazil.
Andrei MorozDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Ana Marisa Fusco AlmeidaDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.
Maria José Soares Mendes-GianniniDepartment of Clinical Analysis, School of Pharmaceutical Sciences, São Paulo State University UNESP, Araraquara, Brazil.ORCID 0000-0002-8059-0826

Funding

Unraveling Cryptococcus neoformans mechanisms of brain invasion and colonizationR01AI145559 · NIAID · UNIVERSITY OF TEXAS EL PASO · PI MARTINEZ, LUIS R · 2019 to 2023
$2.6M
NIAID NIH HHS R01 AI145559
6 · The paper itself

Abstract

Dermatophytes are keratinophilic filamentous fungi that cause dermatophytosis, and the main etiological agents can be anthropophilic and zoophilic. Several virulence factors are involved in the pathogenesis of dermatophytosis, including the formation of fungal biofilms. In this context, three-dimensional (3D) models, such as spheroids and reconstructed human skin (RHS), have gained prominence, as they more accurately emulate fungus-host interactions, closely resembling physiological conditions. Therefore, the present study investigated the biofilm formation of

Indexed as

ArthrodermataceaeBiofilmsTineaTrichophytonFungal ProteinsHumansMicroscopy, ConfocalMicroscopy, Electron, ScanningSkinFungal Proteinsbiofilmsdermatophytesmodels of infectionTrichophyton rubrum

Identifiers

PMID40879668
PMCPMC12502595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.