ArticleMicrobiology spectrum2025
Bispecific antibody engineered from two non-protective antibodies confers full protection against anthrax toxin through inhibition of PA83 cleavage.
Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Ultrapotent neutralization of Bacillus anthracis toxin by a human antibody via blockade of PA oligomerization.PLoS pathogens · 2026Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Anthrax is a highly contagious zoonotic disease, posing a great threat to human life and health. Protective antibodies against anthrax protective antigens (PA) can play a crucial role in the prevention and treatment of anthrax infections. However, the functions and mechanisms of the large number of non-protective antibodies elicited during the infection or vaccination of anthrax have not been clearly understood. Here, we found that two non-protective antibodies, 2A6 and 8A7, exerted an enhanced neutralizing effect both
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.