Evidence map›Paper›PMID 40879392›Full record

ArticlemBio2025

Unculturable bacteria exploit a secretory protein to antagonize insect melanization for persistent infection.

You Li, Yu Du, Dongsheng Ren, Yu Bin, Qian Chen, Taiyun Wei

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

You Li *State Key Laboratory of Agricultural and Forestry Biosecurity, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.ORCID 0000-0001-9952-9542
Yu Du *State Key Laboratory of Agricultural and Forestry Biosecurity, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.
Dongsheng Ren *State Key Laboratory of Agricultural and Forestry Biosecurity, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.
Yu BinState Key Laboratory of Agricultural and Forestry Biosecurity, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.
Qian ChenState Key Laboratory of Agricultural and Forestry Biosecurity, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.ORCID 0000-0002-8442-6089
Taiyun WeiState Key Laboratory of Agricultural and Forestry Biosecurity, Fujian Agriculture and Forestry University, Fuzhou, Fujian, China.ORCID 0000-0002-0732-9752

Funding

Fujian Agriculture and Forestry University 103-722022001National Natural Science Foundation of China 32202395National Natural Science Foundation of China U23A20197
6 · The paper itself

Abstract

Phloem-inhabiting unculturable bacterial pathogens are persistently transmitted by insect vectors. However, how they evade insect immune responses to ensure persistent transmission remains unknown. The important melanization immune response in insects is triggered by cleavage of prophenoloxidase (PPO) into active phenoloxidase (PO) via clip-domain serine proteases (CLIPs). Here, we demonstrate that infection of

Indexed as

Bacterial ProteinsHemipteraInsect VectorsMelaninsRhizobiaceaeAnimalsCarrier ProteinsCatechol OxidaseEnzyme PrecursorsHost-Pathogen InteractionsInsect ProteinsMonophenol MonooxygenasePlant DiseasesSignal TransductionBacterial ProteinsCarrier ProteinsCatechol OxidaseEnzyme PrecursorsInsect ProteinsMelaninsMonophenol Monooxygenasepeptidoglycan recognition proteinpro-phenoloxidaseCandidatus Liberibacter asiaticushuanglongbingmelanizationpersistent infectionpsyllidsecretory protein

Identifiers

PMID40879392
PMCPMC12506112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.