Evidence map›Paper›PMID 40879342›Full record

ArticleWater science and technology : a journal of the International Association on Water Pollution Research2025

Understanding the dynamics of a microbial consortium prior to and post the introduction of specific antiretroviral compounds in a moving bed biofilm reactor system.

Herman Dick Mokgope, Michael John Klink, Tara Aisling Walmsley

Abstract read
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In one paragraph

Article in Water science and technology : a journal of the International Association on Water Pollution Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Herman Dick MokgopeDepartment of Natural Sciences, Vaal University of Technology, Vanderbijlpark Campus, Vanderbijlpark 1911, South Africa.ORCID https://orcid.org/0000-0003-0263-1618
Michael John KlinkDepartment of Natural Sciences, Vaal University of Technology, Vanderbijlpark Campus, Vanderbijlpark 1911, South Africa.ORCID https://orcid.org/0000-0002-9131-6312
Tara Aisling WalmsleyDepartment of Natural Sciences, Vaal University of Technology, Vanderbijlpark Campus, Vanderbijlpark 1911, South Africa E-mail: taraw@vut.ac.za.ORCID https://orcid.org/0000-0003-1142-5648

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of moving bed biofilm reactor (MBBR) systems for the treatment of municipal and industrial wastewater has been shown to gain more attention, in contrast to activated sludge systems. However, little is known about the effects of pharmaceuticals on constituent microbial communities. This study investigated the shift in microbial community compositions of biofilms in an MBBR due to exposure to specific antiretroviral (ARV) compounds. Microbial diversity (alpha-diversity) of seeded sludge from a full-scale municipal wastewater treatment plant and biofilm samples from a laboratory-scale MBBR system during pre- and post-introduction of ARV compounds was investigated by Illumina sequencing of the 16S rRNA gene. Microbial diversity results demonstrated that the introduction of ARV drugs affects the bacterial community composition and diversity considerably. For instance, the genus

Indexed as

Anti-Retroviral AgentsBiofilmsBioreactorsMicrobial ConsortiaBacteriaRNA, Ribosomal, 16SSewageWaste Disposal, FluidAnti-Retroviral AgentsRNA, Ribosomal, 16SSewageantiretroviral drugs (ARVs)microbial community dynamicsmoving bed biofilm reactor (MBBR)wastewater treatment plants (WWTPs)

Identifiers

PMID40879342

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.