Evidence map›Paper›PMID 40879266›Full record

ArticleInternational forum of allergy & rhinology2025

Elezanumab Accelerates Post-Injury Regeneration of Olfactory Sensory Neurons in a Methimazole-Induced Mouse Model.

Eri Mori, Rumi Ueha, Hirotaka Tanaka, Hironobu Nishijima, Masayoshi Kobayashi, Nobuyoshi Otori, Kenji Kondo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International forum of allergy & rhinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Eri MoriDepartment of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0003-3273-3789
Rumi UehaDepartment of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.ORCID 0000-0002-0608-7237
Hirotaka TanakaDepartment of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.
Hironobu NishijimaDepartment of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.
Masayoshi KobayashiDepartment of Otorhinolaryngology-Head and Neck Surgery, Mie University Graduate School of Medicine, Tsu, Japan.
Nobuyoshi OtoriDepartment of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.
Kenji KondoDepartment of Otolaryngology-Head and Neck Surgery, Faculty of Medicine, The University of Tokyo, Tokyo, Japan.

Funding

JSPS KAKENHI 21K09591
6 · The paper itself

Abstract

key pointsElezanumab accelerates olfactory sensory neuron regeneration in a methimazole-induced mouse model. Repulsive guidance molecule A blockade increases GAP43

Indexed as

Antibodies, MonoclonalNerve RegenerationOlfaction DisordersOlfactory Receptor NeuronsAnimalsAntibodies, Monoclonal, HumanizedDisease Models, AnimalGAP-43 ProteinHumansMethimazoleMiceOlfactory Marker ProteinAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedelezanumabGAP-43 ProteinMethimazoleOlfactory Marker ProteinOmp protein, mouseaxonal regenerationelezanumabneuroepithelial regenerationolfactory sensory neuronsregeneration promotion

Identifiers

PMID40879266
PMCPMC12503071

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.