Evidence map›Paper›PMID 40879193›Full record

ReviewThoracic cancer2025

Pure Red Cell Aplasia That Developed 13 Years After Thymoma Treatment: A Case Report and Literature Review.

Kento Kono, Kazuhisa Nakashima, Yukari Tsubata, Tsutomu Takahashi, Keita Kawakado, Takashi Yanagawa, Makoto Nagasaki, Tamio Okimoto, Takeshi Isobe

Abstract readCase ReportsReview
In one paragraph

Review in Thoracic cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kento KonoDepartment of Respiratory Medicine, NHO Hamada Medical Center, Hamada, Shimane, Japan.ORCID https://orcid.org/0000-0001-5974-1741
Kazuhisa NakashimaDepartment of Respiratory Medicine, NHO Hamada Medical Center, Hamada, Shimane, Japan.
Yukari TsubataDepartment of Respiratory Medicine, NHO Hamada Medical Center, Hamada, Shimane, Japan.
Tsutomu TakahashiDepartment of Hematology, Shimane University Hospital, Izumo, Shimane, Japan.ORCID https://orcid.org/0000-0002-8731-3469
Keita KawakadoDepartment of Respiratory Medicine, NHO Hamada Medical Center, Hamada, Shimane, Japan.
Takashi YanagawaDepartment of Respiratory Medicine, NHO Hamada Medical Center, Hamada, Shimane, Japan.
Makoto NagasakiDepartment of Diagnostic Pathology, Shimane Prefectural Central Hospital, Izumo, Shimane, Japan.
Tamio OkimotoDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.
Takeshi IsobeDepartment of Internal Medicine, Division of Medical Oncology and Respiratory Medicine, Shimane University Faculty of Medicine, Izumo, Shimane, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 47-year-old woman was diagnosed with invasive thymoma 13 years ago. She had undergone repeated surgeries, as well as chemotherapy and radiation therapy. Chemotherapy was discontinued after the patient developed normocytic anemia, which was unresponsive to repeated blood transfusions. Bone marrow biopsy results revealed pure red cell aplasia (PRCA). Cyclosporine treatment led to improvement in PRCA; however, the patient died 3 years later from an invasive pneumococcal infection. The onset of thymoma-associated PRCA remains unpredictable, and a significant delay may occur between the diagnosis of the two conditions.

Indexed as

Red-Cell Aplasia, PureThymomaThymus NeoplasmsFemaleHumansMiddle Agedcyclosporinepure red cell aplasiathymoma

Identifiers

PMID40879193
PMCPMC12395460

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.