ArticleEuropace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology2025
Impact of timing of treatment for cardiac implantable electronic device infections on healthcare utilization and expenditures.
Article in Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Cost-effectiveness modelling of early lead extraction for cardiac implantable electronic device infections in the United Kingdom.BMJ open · 2026Article
- Clinical characteristics, treatment, and outcomes in CIED-related vs. left-sided infective endocarditis: a nationwide study from the NIDUS registry.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Contemporary practice about cardiac implantable electronic device infections prevention: A French multicenter survey.Heart rhythm O2 · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
aimsEarly extraction for cardiovascular implantable electronic device (CIED) infections has been associated with longer survival, while the impact on healthcare utilization is unknown. The aim is to evaluate the impact of early extraction on healthcare expenditures and utilization. METHODS AND
resultsUsing 100% Medicare fee-for-service data with Part D from 1/1/2006 through 12/31/2019, patients with a de novo CIED implant and CIED infection > 12 months after implant were identified to analyse healthcare utilization according to the occurrence and timing of extraction. The CIED infection was defined as (i) a claim for endocarditis or infection of a device implant and (i) documented antibiotic therapy. Among 9594 patients with CIED infection [median age 75 years (25th, 75th; 67, 81), 39.9% women], 7819 (81.5%) patients did not undergo extraction within 30 days, 1277 (13.3%) patients had extraction in <7 days, and 498 (5.2%) patients underwent extraction between 7 and 30 days. Following multivariable adjustment, extraction in less than 7 days (adjusted hazard ratio 0.79, 95% confidence interval 0.72-0.85, P < 0.001) of CIED infection was associated with lower all-cause hospitalization in follow-up. Healthcare expenditures in the year following CIED infection were higher among the patients without extraction within 30 days (median $63 425; 25th, 75th $22,853, $120 273) and were lowest among patients who underwent extraction < 7 days after diagnosis of CIED infection (median $36 824; 25th, 75th $12,748, $77 772).
conclusionExtraction was associated with lower hospitalization and lower healthcare expenditures in the year following CIED infection management period. Early extraction was associated with optimal healthcare utilization and expenditures.
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