Evidence map›Paper›PMID 40879105›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2025

The Kinesin Motor Kif9 Disrupts Primary Cilia Length by Mispositioning Centriolar Satellites.

Juan Jesus Vicente, Jacob Weiss, Michael Wagenbach, Linda Wordeman

Abstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The Kinesin Motor Kif9 Disrupts Primary Cilia Length by Mispositioning Centriolar Satellites.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Juan Jesus VicenteDepartment of Neurobiology & Biophysics, University of Washington School of Medicine, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-3402-3046
Jacob WeissUniversity of Colorado Boulder, Boulder, Colorado, USA.
Michael WagenbachDepartment of Neurobiology & Biophysics, University of Washington School of Medicine, Seattle, Washington, USA.
Linda WordemanDepartment of Neurobiology & Biophysics, University of Washington School of Medicine, Seattle, Washington, USA.ORCID https://orcid.org/0000-0002-9444-0650

Funding

Microtubule dynamics and error correctionR01GM145567 · NIGMS · UNIVERSITY OF WASHINGTON · PI WORDEMAN, LINDA · 2022 to 2025
$1.8M
National Institutes of Health (NIH) GM145567National Science Foundation (NSF) 2319918NIGMS NIH HHS R01 GM145567University of Washington (UW)
6 · The paper itself

Abstract

Primary cilia are nonmotile, microtubule-based structures on the surface of most vertebrate cells, acting as sensory hubs to regulate cellular responses. Their formation, maintenance, and disassembly are tightly regulated, with dysfunction linked to diseases like ciliopathies, cancer, and neurological disorders. Centriolar satellites (CS), membrane-less granules around the centrosome, are involved in protein trafficking to and from the centrosome and centrosomal function, and regulate primary cilia. We show that Kif9 loss causes CS aggregation near the centrosome, leading to defects in cilia length and altering the levels of key primary cilia proteins like TALPID3, CEP131, CEP170, and CEP290.

Indexed as

CentriolesCiliaKinesinsAnimalsCentrosomeHumansKinesinscentriolar satellitescentrosomekinesinmicrotubulesprimary cilia

Identifiers

PMID40879105
PMCPMC12257439

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.