ArticleJournal of the American Heart Association2025
Validation of the GERAADA Score for Predicting 30-Day Mortality Rate in Acute Type A Aortic Dissection: A Single-Center Study in China.
Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Centroid Regression for Preoperative Risk Assessment of Acute Type A Aortic Dissection Based on Multivariate Clinical Data.Journal of clinical medicine · 2026Article
- Analysis of epidemiological characteristics and prognosis based on 1,343 cases of aortic dissection from a regional single center.Frontiers in cardiovascular medicine · 2026Article
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6 authors.
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Abstract
backgroundThis study aimed to validate the predictive performance of the GERAADA (German Registry for Acute Type A Aortic Dissection) score in predicting 30-day mortality rate in patients with acute type A aortic dissection in China.
methodsWe retrospectively analyzed 526 patients who underwent surgical treatment for acute type A aortic dissection at our institution between 2018 and 2021. The predictive performance of the GERAADA score was evaluated using calibration (observed-to-expected ratio and Hosmer-Lemeshow test) and discrimination (area under the receiver operating characteristic curve). Logistic regression analysis was performed to identify risk factors of 30-day mortality rate. Stratified analyses were conducted to assess performance across different risk categories.
resultsThe cohort exhibited distinct characteristics, including younger age, longer intervals from onset to admission, and more extensive aortic arch procedures. The GERAADA score demonstrated good calibration (Hosmer-Lemeshow test,
conclusionsThis study validated the GERAADA score in China for predicting mortality risk in patients with acute type A aortic dissection, showing strong performance in discrimination and calibration. We also developed a mortality risk assessment strategy based on the GERAADA score, offering a practical framework for clinical use. The modular design allows for easy adaptation across centers, although further multicenter studies are needed to confirm its generalizability.
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