Evidence map›Paper›PMID 40878907›Full record

ReviewJournal of cosmetic dermatology2025

The Use of Light-Based Therapies in the Treatment of Alopecia.

Robert J Vanaria, Aysham Chaudry, Mark S Nestor

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Robert J VanariaCenter for Clinical and Cosmetic Research, Aventura, Florida, USA.
Aysham ChaudryCenter for Clinical and Cosmetic Research, Aventura, Florida, USA.ORCID https://orcid.org/0009-0005-5303-5850
Mark S NestorCenter for Clinical and Cosmetic Research, Aventura, Florida, USA.ORCID https://orcid.org/0000-0002-8978-7932

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlopecia encompasses a group of conditions that can significantly impact quality of life, especially among women and younger individuals. While pharmaceutical therapies remain the cornerstone of treatment, laser and light-based therapies, especially low-level light therapy (LLLT), offer promising noninvasive alternatives. LLLT uses specific wavelengths of light to stimulate hair follicle repair, prolong the hair growth phase, and promote regrowth. Recent advancements in at-home devices and dual-wavelength LED systems have expanded access to these therapies. This review explores the role of LLLT in treating alopecias, evaluating its mechanisms, efficacy, and clinical applications.

methodsA PubMed search using terms related to alopecia and laser/light therapy was conducted. Results were limited to English-only articles from 2020 to 2025, excluding duplicates. Additional articles were identified through citation tracking. Studies not focused on light-based therapies were excluded.

resultsOf 403 articles identified, 63 were included based on relevance to alopecia or hair loss and light-based therapy. Results were categorized by treatment modality and type of hair loss, with overlap between categories. DISCUSSION: This review highlights the growing role of LLLT as an adjunct or alternative treatment for various types of alopecia. In androgenetic alopecia, LLLT improves hair density and follicular responsiveness, with enhanced outcomes when combined with minoxidil or finasteride. For telogen effluvium, LLLT shows potential in prolonging the anagen phase and reducing shedding, although larger studies are needed. In alopecia areata, LLLT may promote regrowth by modulating immune responses and improving perifollicular microcirculation. Emerging data also support LLLT in lichen planopilaris and central centrifugal alopecia (CCCA), with case reports showing reduced inflammation and hair regrowth. Overall, LLLT offers a noninvasive, well-tolerated option across alopecia subtypes, though standardized protocols and long-term data remain limited.

Indexed as

AlopeciaLow-Level Light TherapyCombined Modality TherapyFinasterideHairHair FollicleHumansMinoxidilQuality of LifeTreatment OutcomeFinasterideMinoxidilalopeciahair losslow level light therapyphotobiomodulation

Identifiers

PMID40878907
PMCPMC12395542

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.