Evidence map›Paper›PMID 40878894›Full record

ArticleJournal of agricultural and food chemistry2025

Genotype-Driven Proteomic Diversity in Macadamia Nuts: Implications for Allergenicity, Nutritional Quality, and Breeding Strategies.

Qi Guo, Bronwyn J Barkla, Regan Barker, Lei Liu

Abstract read
In one paragraph

Article in Journal of agricultural and food chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Dietary Supplementation ofMicroorganisms · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qi GuoSouthern Cross Plant Science, Faculty of Science and Engineering, Southern Cross University, Lismore, NSW 2480, Australia.ORCID 0000-0002-3528-2533
Bronwyn J BarklaSouthern Cross Plant Science, Faculty of Science and Engineering, Southern Cross University, Lismore, NSW 2480, Australia.
Regan BarkerSouthern Cross Plant Science, Faculty of Science and Engineering, Southern Cross University, Lismore, NSW 2480, Australia.
Lei LiuSouthern Cross Plant Science, Faculty of Science and Engineering, Southern Cross University, Lismore, NSW 2480, Australia.ORCID 0000-0003-3719-9204

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Macadamia nuts are valued for their nutritional content, yet little is known about the factors that affect nut quality or the genetic contributions of parental lines. This study optimized a protein extraction protocol for lipid-rich macadamia nuts and applied SDS-PAGE and mass spectrometry-based proteomics to characterize nuts with known parental origin. A total of 431 high-confidence proteins were identified, with seed storage proteins (SSPs), primarily vicilin- and legumin-like globulins, comprising nearly 50% of total protein abundance. Distinct SDS-PAGE banding patterns among genotypes, including within maternal lines, indicated significant paternal influence on protein profiles. Correlation analysis confirmed that specific gel bands reveal the abundance of allergenic SSPs. Moreover, sequence coverage and post-translational modifications of SSPs varied across genotypes, indicating molecular divergence. These findings provide insights into the genetic basis of nut protein composition, inform allergenicity risk assessment, and support breeding strategies aimed at improving macadamia nut quality and developing hypoallergenic cultivars.

Indexed as

MacadamiaNutritive ValuePlant BreedingAllergensChromatography, High Pressure LiquidGenetic VariationGenome, PlantGenotypeLiquid Chromatography-Mass SpectrometryNutsPlant ProteinsProteomeProteomicsSeed Storage ProteinsAllergensPlant ProteinsProteomeSeed Storage Proteinsallergengenotype-dependent variationhypoallergenic cultivar developmentkernelleguminMacadamia integrifoliaseed proteomevicilin

Identifiers

PMID40878894
PMCPMC12429045

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.