Evidence map›Paper›PMID 40878837›Full record

ArticleACR open rheumatology2025

Effects of Audio-Guided Imagery on Raynaud Phenomenon in Connective Tissue Disease.

Cristina Padilla, Veena Katikineni, Yongseok Park, Leigh Freno, Maureen Laffoon, Lee Reichbaum, Robert Lafyatis, Robyn Domsic

Abstract read
In one paragraph

Article in ACR open rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cristina PadillaUniversity of Pittsburgh, Pittsburgh, Pennsylvania.ORCID https://orcid.org/0000-0001-9548-5263
Veena KatikineniUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Yongseok ParkUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Leigh FrenoUniversity of Pittsburgh Medical Center Arthritis and Autoimmunity Center, Pittsburgh, Pennsylvania.
Maureen LaffoonUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Lee ReichbaumUniversity of Pittsburgh and University of Pittsburgh Medical Center Shadyside Hospital, Pittsburgh, Pennsylvania.
Robert LafyatisUniversity of Pittsburgh, Pittsburgh, Pennsylvania.
Robyn DomsicUniversity of Pittsburgh, Pittsburgh, Pennsylvania.ORCID https://orcid.org/0000-0002-2765-0922

Funding

Translational studies for identifying and targeting novel pathways in systemic sclerosis pathogenesisP50AR060780 · NIAMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAFYATIS, ROBERT A. · 2011 to 2021
$14.9M
NIAMS NIH HHS P50 AR060780
6 · The paper itself

Abstract

objectiveTo assess the physical, emotional, and mental impact of regular audio-guided imagery (AGI) in patients with connective tissue disease (CTD)-associated Raynaud phenomenon (RP).

methodsSixteen adult patients with CTD-associated RP were enrolled in an open-label, single-arm, eight-week intervention with daily AGI at a single center. Patients completed surveys, including assessment of RP severity, depression/anxiety, and quality of life at baseline and the end of eight weeks.

resultsStudy participants demonstrated significant improvement in all patient reported outcomes, except Generalized Anxiety Disorder 7, which showed improvement but was not statistically significant. This eight-week intervention shows that patients with CTD-associated RP had less severe RP episodes, as well as improved quality of life and depressive symptoms.

conclusionAGI significantly improved several domains of health, including physical, emotional, and mental, in patients with CTD-associated RP who otherwise more commonly struggle with more RP attacks, lower quality of life, and depression. AGI is a low-cost, low-risk, and convenient therapy for CTD-associated RP. A larger study studying the effects of this intervention is indicated.

Identifiers

PMID40878837
PMCPMC12305345

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