Evidence map›Paper›PMID 40878758›Full record

ArticleCancer medicine2025

Anticipated Out-Of-Pocket Costs and Prostate Cancer Management Among Men With Commercial Insurance.

Sarah Leick, Addison Shay, Samuel R Kaufman, Xiu Liu, Paula Guro, Preeti Chachlani, Mary Oerline, Christopher Dall, Dawson C Hill, Avinash Maganty and 3 more

Abstract read
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sarah LeickDepartment of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Addison ShayDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0003-1651-317X
Samuel R KaufmanDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.
Xiu LiuDepartment of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Paula GuroDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0009-0002-0103-5734
Preeti ChachlaniDepartment of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Mary OerlineDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.
Christopher DallDepartment of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Dawson C HillDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.
Avinash MagantyDepartment of Urology, Massachusetts General Hospital, Boston, Massachusetts, USA.
Vahakn B ShahinianDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.
Brent K HollenbeckDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.
Arnav SrivastavaDow Division of Health Services Research, Department of Urology, University of Michigan, Ann Arbor, Michigan, USA.ORCID https://orcid.org/0000-0002-9772-1415

Funding

Advanced Training in Urologic OncologyT32CA180984 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Ganesh S Palapattu, VAHAKN B SHAHINIAN · 2014 to 2026
$3.4M
Urology practice consolidation and care for men with prostate cancerR01CA279746 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BRENT K. HOLLENBECK, Andrew M Ryan · 2024 to 2026
$1.8M
NCI NIH HHS R01 CA279746NCI NIH HHS T32 CA180984
6 · The paper itself

Abstract

introductionMen with newly diagnosed prostate cancer often appropriately elect for either immediate treatment or conservative management. The out-of-pocket costs they face vary by management strategy, with immediate treatment often superseding those of conservative management, potentially influencing patient decisions. We estimated the anticipated out-of-pocket costs that commercially insured men with newly diagnosed prostate cancer face and measured their association with immediate treatment.

methodsFrom MarketScan, we identified men with newly diagnosed prostate cancer from 2010-2020. Separately, using actual out-of-pocket costs (summing deductible, copay, coinsurance) among patients undergoing arthroscopic meniscal repair (n = 383,187), we derived regression coefficients for patient-level variables (e.g., health plan type) that inform their financial liability. We applied these coefficients to men with prostate cancer and estimated their predicted out-of-pocket costs, our main exposure. We sorted patients into quartiles and used logistic regression to calculate adjusted probabilities of immediate treatment (versus conservative management).

resultsWe identified 58,206 men with prostate cancer and rank ordered them by predicted out-of-pocket cost. Approximately 12% of men had a predicted out-of-pocket cost of zero, and among those with non-zero cost sharing, the median out-of-pocket cost was $350 (IQR: $275, $486). Across quartiles of predicted out-of-pocket costs, adjusted percentages of immediate treatment were in a narrow range between 77.8% (95% CI: 76.8%, 78.8%) for Quartile 1% and 78.6% (95% CI: 77.7%, 79.5%) for Quartile 4.

conclusionAmong commercially insured men with prostate cancer, predicted out-of-pocket costs varied substantially. However, the choice of management, immediate treatment or conservative management, appears insensitive (i.e., inelastic) to patient anticipated financial liability.

Indexed as

Health ExpendituresInsurance, HealthProstatic NeoplasmsAgedConservative TreatmentHumansMaleMiddle AgedUnited Statesfinancial toxicityinsurance designout‐of‐pocket costsprostate cancer

Identifiers

PMID40878758
PMCPMC12395269

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.