Clinical characteristics and all-cause mortality in female patients with idiopathic pulmonary fibrosis in Chinese population.

Aiyuan Zhou, Qing Song, Rongli Lu, Dingding Deng, Yi Li, Xiyan Zhang, Pinhua Pan

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Article in Journal of global health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Aiyuan ZhouDepartment of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Centre for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Qing SongDepartment of Respiratory and Critical Care Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Rongli LuDepartment of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Centre for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Dingding DengDepartment of Respiratory and Critical Care Medicine, First Affiliated People's Hospital of Shaoyang University, Shaoyang, Hunan, China.

Yi LiDepartment of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Centre for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Xiyan ZhangDepartment of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Centre for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Pinhua PanDepartment of Respiratory Medicine, National Key Clinical Specialty, Branch of National Clinical Research Centre for Respiratory Disease, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Idiopathic pulmonary fibrosis (IPF) exhibits notable sex-based disparities and male patients with IPF are significantly more numerous than female patients. Therefore, the female patients are often overlooked and under-investigated. This study aimed to evaluate the clinical characteristics and all-cause mortality in female patients with IPF in Chinese population. Methods: This retrospective cohort study included IPF patients registered at Xiangya Hospital of Central South University and the First Affiliated People's Hospital of Shaoyang University from January 2015 to May 2024. The data on age, sex, body mass index, smoking (pack-years), forced expiratory volume in one second to forced vital capacity, diffusing capacity of the lung for carbon monoxide percentage of predicted (DL Results: A total of 583 patients were enrolled and 116 (19.9%) of them were female. Female patients had higher levels of forced expiratory volume in one second to forced vital capacity, DL Conclusions: Significant differences in clinical characteristics and prognosis were observed between male and female IPF patients in Chinese population. Specifically, female patients exhibited better pulmonary function, higher Pao

Indexed as

Idiopathic Pulmonary FibrosisAgedCause of DeathChinaEast Asian PeopleFemaleHumansMiddle AgedRetrospective StudiesSex Factors

Identifiers

PMID40878468

DOI10.7189/jogh.15.04246

PMCPMC12395208

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