Evidence map›Paper›PMID 40878460›Full record

ArticleAnimal bioscience2026

Population structure and genome-wide association study of body conformation traits of two native goat breeds in China.

Rong Yang, Di Zhou, Yanli Lv, Xingzhou Tian, Liqun Ren, Fu Wang, Zhengang Guo, Yongju Zhao, Jipan Zhang

Abstract read
In one paragraph

Article in Animal bioscience, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Rong YangGuizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, China.
Di ZhouGuizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, China.
Yanli LvGuizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, China.
Xingzhou TianCollege of Animal Science, Guizhou University, Guiyang, China.
Liqun RenGuizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, China.
Fu WangGuizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, China.
Zhengang GuoGuizhou Provincial Breeding Livestock and Poultry Germplasm Determination Center, Guiyang, China.
Yongju ZhaoCollege of Animal Science and Technology, Southwest University, Chongqing, China.
Jipan ZhangCollege of Animal Science and Technology, Southwest University, Chongqing, China.

Funding

Guizhou Province 033Guizhou Provincial Department of Agriculture and Rural Affairs
6 · The paper itself

Abstract

objectiveBody conformation traits directly impact carcass performance in the meat goat industry. This study explored the population genetics of two Chinese goat breeds and identified the genomic variants associated with their body conformation traits.

methodsThe Guizhou black goat (GBG, n = 104) and Hezhang black goat (HBG, n = 100) underwent genotyping through whole-genome sequencing and phenotyping by measuring their body height (BH), body length (BL), chest depth (CD), chest width (CW), chest girth (CG), rump width (RW), rump height (RH), and cannon circumference (CC).

resultsThe relatedness analysis showed that these goats exhibited low genetic kinship-related, with the GBG and HBG being relatively independent, albeit with some genetic introgression present. The lambda values showed that the reliability of the genome-wide association studies (GWAS) model, identifying a total of 33, 1, 6, 2, 5, 10, 21, and 13 single nucleotide polymorphisms (SNPs) as significantly correlated (p<8.33e-8) with BH, BL, CD, CW, CG, RW, RH, and CC, respectively. The GWAS for BH and RH identified the greatest number of significant SNPs, with a substantial overlap among them, mainly located in four regions: chr13_63286230-69784740 (10 SNPs), chr14_60354209-60376549 (six SNPs), and chr15_65605417-73873841 (five SNPs), and chr23_42819635-43332716 (nine SNPs). Individuals with a greater number of these SNPs displayed elevated BH and RH values. Following the annotation of all significant SNPs, 102 genes within a ±100 Kb region were identified. The most significantly enriched KEGG pathway was "Olfactory transduction", while the most significantly enriched GO terms included "cellular process" and "molecular transducer activity".

conclusionThis study investigated the population genetics of two prominent Chinese goat breeds and identified several SNPs that are significantly associated with body conformation traits. These findings offer biological insights into enhancing growth performance and hold significant potential for practical application in the genomic selection of meat goats.

Indexed as

Body Conformation TraitGenome-wide Association StudyGoatPopulation StructureSingle Nucleotide Polymorphism

Identifiers

PMID40878460
PMCPMC12754489

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