Evidence map›Paper›PMID 40878357›Full record

ArticleAllergy2025

Unsupervised Clustering Reveals Intestine-Adapted Eosinophil Subsets Shaped by Local Inflammation.

Leigha D Larsen, Arman Kian, Natalie A Falta, Barbara Fox, Lisa A Spencer

Abstract readLetter
In one paragraph

Article in Allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Tissue adaptation of eosinophils.Journal of leukocyte biology · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Leigha D LarsenDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Arman KianDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID https://orcid.org/0009-0000-3584-7461
Natalie A FaltaDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Barbara FoxDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.
Lisa A SpencerDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.ORCID https://orcid.org/0000-0002-2365-9559

Funding

Cellular and molecular mechanisms of mucosal organ crosstalk in allergic diseasesR01AI168134 · NIAID · UNIVERSITY OF COLORADO DENVER · PI SPENCER, LISA ANN · 2022 to 2025
$1.9M
Novel Roles for Mucosal Tissue Eosinophils in Dissemination of Type 2 ImmunityR01AI198286 · NIAID · UNIVERSITY OF COLORADO DENVER · PI Lisa Ann Spencer · 2026 to 2026
$763k
Eosinophil functions in allergic gastrointestinal diseasesR56AI121186 · NIAID · UNIVERSITY OF COLORADO DENVER · PI SPENCER, LISA ANN · 2024 to 2024
$195k
Crohn's and Colitis FoundationNational Institute of Allergy and Infectious DiseasesNIAID NIH HHS R01 AI168134NIAID NIH HHS R01 AI198286NIAID NIH HHS R56 AI121186
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

animal modelseosinophilsinflammationinnate immunitymucosal immunity

Identifiers

PMID40878357
PMCPMC12486345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.