Evidence map›Paper›PMID 40877930›Full record

ArticleBMC veterinary research2025

Effects of dietary supplementation of organic and inorganic zinc on the performance characteristics, tissue mineralization, apparent mineral retention, and antioxidant status of broiler chicks.

Bruno Reis de Carvalho, Pedro Righetti Arnaut, Jorge Cunha Lima Muniz, Hélvio da Cruz Ferreira, Nathana Rudio Furlani, Warley Júnior Alves, James Eugene Pettigrew, Melissa Izabel Hannas, Gabriel da Silva Viana

Abstract read
In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bruno Reis de CarvalhoDepartment of Animal Science, Federal University of Viçosa, Viçosa, 36570-900, Minas Gerais, Brazil.
Pedro Righetti ArnautDepartment of Animal Science, Federal University of Viçosa, Viçosa, 36570-900, Minas Gerais, Brazil.
Jorge Cunha Lima MunizDepartment of Animal Science, Federal University of Viçosa, Viçosa, 36570-900, Minas Gerais, Brazil.
Hélvio da Cruz FerreiraDepartment of Animal Science, Federal University of Viçosa, Viçosa, 36570-900, Minas Gerais, Brazil.
Nathana Rudio FurlaniDepartment of Animal Science, Federal University of Viçosa, Viçosa, 36570-900, Minas Gerais, Brazil.
Warley Júnior AlvesDepartment of Animal Science, Federal University of Viçosa, Viçosa, 36570-900, Minas Gerais, Brazil.
James Eugene PettigrewPettigrew Research Services US, Champaign, IL, USA.
Melissa Izabel HannasDepartment of Animal Science, Federal University of Viçosa, Viçosa, 36570-900, Minas Gerais, Brazil. melissa.hannas@ufv.br.
Gabriel da Silva VianaProduction Systems, Natural Resources Institute Finland (Luke), Jokioinen, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 10-day study was carried out to evaluated the effects of organic (zinc proteinate, ZnPro) and inorganic (zinc sulfate, ZnSO₄•H₂O) zinc supplementation on growth, tissue mineralization, mineral excretion, and antioxidant responses in broiler chickens. Male Cobb 500 chicks were allotted into 10 treatments, and ten replicates per treatment with five birds per replicate in a 2 × 5 factorial design. Dietary Zn was supplied at 0, 19, 38, 57, and 76 mg/kg. ZnPro feeds included proteinates for copper, iron, and manganese, while Zn-sulfate diets used inorganic salts. Results Body weight (BW) and average daily gain (ADG) improved at 19 mg Zn/kg for both sources. Feed conversion ratio (FCR) was optimized at 19 mg Zn/kg for ZnPro and 30 mg Zn/kg for Zn-sulfate. Interactive effect was observed for Zn intake, excretion and retention. At higher inclusion of ZnPro levels (≥ 38 mg Zn/kg), chicks showed increased Zn intake and excretion. ZnPro levels higher than ≥ 56 mg Zn/kg promoted higher Zn retention. Zn retention in liver and tibia were maximized at 38 mg Zn/kg for both sources, and were similar until 76 mg Zn/kg. ZnPro resulted in higher liver Zn concentration and greater tibia manganese (Mn) deposition, while Zn-sulfate increased liver iron (Fe) concentration. Additionally, Zn-sulfate enhanced glutathione peroxidase (GSH-Px) activity in liver and breast muscle, while both sources modulated liver superoxide dismutase (SOD) activity. Conclusions Both Zn sources supported growth and antioxidant responses, with optimal DWG levels at 30 mg Zn/kg for Zn-sulfate and 19 mg Zn/kg for ZnPro, highlighting greater efficiency of the organic source. Inorganic Zn further boosted GSH-Px activity, enhancing tissue antioxidant capacity, while ZnPro demonstrated advantages in tissue mineral retention. Further research on environmental impacts of Zn excretion from high ZnPro diets is recommended.

Indexed as

AntioxidantsCalcification, PhysiologicChickensDietary SupplementsZincAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsDietMaleMineralsAntioxidantsMineralsZincAntioxidant defenseMineral retentionTrace mineral requirement

Identifiers

PMID40877930
PMCPMC12392474

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.