Evidence map›Paper›PMID 40877867›Full record

ArticleBMC neurology2025

Use of MRI-double inversion recovery sequence for early diagnosis of multiple sclerosis: case series.

Dan Zhu, Yongjia Shao, Nana Zhang, Zhourui Wu, Liming Cheng, Hongyu Zhou, ShuGuang Chu

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dan Zhu *Department of Radiology, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Pudong New Area, Shanghai, 200120, China.
Yongjia Shao *Department of Radiology, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Pudong New Area, Shanghai, 200120, China.
Nana ZhangDepartment of Neurology, West China Hospital, Sichuan University, No.37 Guo Xue Xiang, Chengdu, 610041, Sichuan Province, China.
Zhourui WuDepartment of Orthopedics, Tongji Hospital Affiliated to Tongji University, Shanghai, China.
Liming ChengDepartment of Orthopedics, Tongji Hospital Affiliated to Tongji University, Shanghai, China.
Hongyu ZhouDepartment of Neurology, West China Hospital, Sichuan University, No.37 Guo Xue Xiang, Chengdu, 610041, Sichuan Province, China. zhouhy@scu.edu.cn.
ShuGuang ChuDepartment of Radiology, Shanghai East Hospital, Tongji University School of Medicine, No. 150 Jimo Road, Pudong New Area, Shanghai, 200120, China. chushu1018@hotmail.com.

Funding

National Key R&D Program of China 2024YFA1108200Pudong New Area Science and Technology Development Fund-Livelihood Research Fund PKJ2020-Y24the Discipline Construction of Health System in Pudong New Area, Shanghai PWzbr2022-14
6 · The paper itself

Abstract

The choice of additional Double Inversion Recovery (DIR) Magnetic Resonance Imaging (MRI) sequences may affect the judgment of the presence and nature of lesions. Herein, we reported three cases initially presenting with non-typical multiple sclerosis (MS) symptoms, in which the final diagnosis of MS was confirmed after incorporating spinal cord and brain DIR MRI sequence. The sequence revealed more conspicuous lesions compared to conventional T2-weighted imaging or T2-weighted fluid-attenuated inversion recovery (T2WI/FLAIR) sequences. Consequently, the patients received an earlier definitive diagnosis and timely treatment. Our cases demonstrated the additional DIR sequences for the patients with non-typical MS symptoms were reasonable and may be helpful.

Indexed as

BrainMagnetic Resonance ImagingMultiple SclerosisSpinal CordAdolescentAdultEarly DiagnosisFemaleHumansMaleDouble inversion recovery sequenceMagnetic resonance imagingMultiple sclerosis

Identifiers

PMID40877867
PMCPMC12395631

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.