Evidence map›Paper›PMID 40877856›Full record

ArticleBMC health services research2025

Geographic and socioeconomic differences in potentially inappropriate medication among older adults - applying a simplified analysis of individual heterogeneity and discriminatory accuracy (AIHDA) for basic comparisons of healthcare quality.

Johan Öberg, Kani Khalaf, Raquel Perez-Vicente, Kristina Johnell, Johan Fastbom, Juan Merlo

Abstract read
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Article in BMC health services research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Johan ÖbergUnit for Social Epidemiology, Faculty of Medicine, Lund University, Malmö, Sweden. johan.oberg@med.lu.se.ORCID http://orcid.org/0000-0002-0701-5155
Kani KhalafUnit for Social Epidemiology, Faculty of Medicine, Lund University, Malmö, Sweden.ORCID http://orcid.org/0000-0002-6749-7037
Raquel Perez-VicenteUnit for Social Epidemiology, Faculty of Medicine, Lund University, Malmö, Sweden.ORCID http://orcid.org/0000-0002-6273-1656
Kristina JohnellDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-0093-7699
Johan FastbomAging Research Center, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-9656-4668
Juan MerloUnit for Social Epidemiology, Faculty of Medicine, Lund University, Malmö, Sweden.ORCID http://orcid.org/0000-0001-8379-9708

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMonitoring of healthcare quality is typically focused on differences between group averages in relation to a desirable benchmark. However, we need to consider (i) the existence of interconnected socioeconomic axes of inequality like age, sex, income, and country of birth and (ii) individual heterogeneity around group averages. Additionally, (iii) we need clear criteria to quantify group differences. By applying the framework analysis of individual heterogeneity and discriminatory accuracy (AIHDA) on an established quality indicator (potentially inappropriate medication (PIM)), we illustrate how to achieve these improvements and how to avoid both unnecessary group stigmatization and false expectations.

methodsWe analyzed 731,339 individuals, ≥ 75-year-old belonging to 36 socioeconomic strata defined by the intersection of age, sex, income, and country of birth, who were alive and residing in the 21 regions Swedish during 2011. We calculated PIM prevalences and evaluate the discriminatory accuracy (DA) of the socioeconomic and geographical group differences using the area under the ROC curve (AUC). The benchmark value was defined as a prevalence of 19%.

resultsIn Sweden, the prevalence of PIM was 24% among ≥ 75-year-olds and regionally it ranged between 21% and 27%. Immigrant 80-84-year-old women with low income had the highest prevalence (29%). All strata including women had higher prevalence than those including men. However, the regional (AUC = 0.520) and socioeconomic (AUC = 0.544) differences were very small. For instance, in the five socioeconomic strata with the lowest prevalence there were about 8,000 more cases of PIM than in the five strata with the highest prevalence of PIM.

conclusionThe prevalence of PIM was higher than the desired benchmark value. There were disparities between group averages, but overall, the regional and socioeconomic differences were very small as informed by their low AUC values. Therefore, interventions to reduce PIM in Sweden should be universal rather than only targeted at the regions and socioeconomic strata with the highest PIM prevalence.

Indexed as

Healthcare DisparitiesInappropriate PrescribingPotentially Inappropriate Medication ListQuality of Health CareAgedAged, 80 and overFemaleHumansMaleQuality Indicators, Health CareSocioeconomic FactorsSwedenEpidemiological methodsHealth care quality assessmentHealth services evaluationMeSHPharmacoepidemiologySocial epidemiology

Identifiers

PMID40877856
PMCPMC12395699

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.