Evidence map›Paper›PMID 40877851›Full record

ArticleBMC biology2025

Genetic stability in the lower Yangtze River basin from Song to Qing Dynasty.

Haifeng He, Xinyuan Kong, Le Tao, Liangsai Zhu, Xuanbo Wang, Mengting Xu, Yuanming Chen, Kongyang Zhu, Yu Xu, Haodong Chen and 8 more

Abstract readHistorical Article
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Haifeng He *State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, 361005, China.
Xinyuan Kong *School of Geography Science, Nanjing Normal University, Nanjing, 210023, China.
Le Tao *Ministry of Education Key Laboratory of Contemporary Anthropology, Center for Evolutionary Biology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Liangsai Zhu *Lianyungang Institute of Cultural Relics Protection and Archaeology, Lianyungang, 222023, China.
Xuanbo WangSuqian Institute of Cultural Relics Protection and Archaeology, Suqian, 223821, China.
Mengting XuState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, 361005, China.
Yuanming ChenLianyungang Institute of Cultural Relics Protection and Archaeology, Lianyungang, 222023, China.
Kongyang ZhuState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, 361005, China.
Yu XuState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, 361005, China.
Haodong ChenMinistry of Education Key Laboratory of Contemporary Anthropology, Center for Evolutionary Biology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Hao MaState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, 361005, China.
Rui WangMinistry of Education Key Laboratory of Contemporary Anthropology, Center for Evolutionary Biology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, 200438, China.
Xiaomin YangFujian Provincial Key Laboratory of Philosophy and Social Sciences in Bioanthropology, Institute of Anthropology, Xiamen University, Xiamen, 361005, China.
Tianyou BaiState Key Laboratory of Cellular Stress Biology, School of Life Sciences, Xiamen University, Xiamen, 361005, China.
Jianxin GuoState Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650201, China.
Yang YangCollege of Marine Life Sciences, Institute of Evolution and Marine Biodiversity, Ocean University of China, Qingdao, 266003, China.
Xin JiaSchool of Geography Science, Nanjing Normal University, Nanjing, 210023, China. jiaxin@njnu.edu.cn.
Chuan-Chao WangMinistry of Education Key Laboratory of Contemporary Anthropology, Center for Evolutionary Biology, Department of Anthropology and Human Genetics, School of Life Sciences, Fudan University, Shanghai, 200438, China. chuanchaowang@fudan.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lower Yangtze River basin holds a pivotal role in Chinese history. As previous genetic research in this region has primarily focused on modern population datasets, the limited availability of ancient human genomes has hindered our capacity to reconstruct detailed ancient population histories and evaluate the genetic impact of Yellow River-related groups. 

resultsHere, we present the first set of ancient human genomes from the lower Yangtze River basin, comprising eight individuals from the Song to Qing Dynasties (960-1921 CE). We observed a high degree of genetic homogeneity in most samples, suggesting long-term regional genetic stability. Seven individuals were estimated to derive 69.3-100% of their ancestry from ancient Yellow River-related populations, while the remainder can be attributed to a southern East Asian substrate. Contemporary Han Chinese residing in the lower Yangtze basin can be modelled as direct genetic descendants of historical individuals from this area. Notably, one Qing Dynasty sample reveals a genetic link to the Eastern Mediterranean.

conclusionsOur findings illustrate enduring genetic continuity in the lower Yangtze River basin throughout historical times. These findings underscore the region's role as a genetic bridge between northern and southern East Asia, retaining local rice-farming ancestry while being shaped by southward expansions of Yellow River-related ancestry.

Indexed as

Asian PeopleGenetics, PopulationGenome, HumanGenomic InstabilityChinaDNA, AncientGenetic VariationHistory, AncientHumansRiversDNA, AncientHistorical JiangsuPopulation historyRice farming-related ancestryThe lower Yangtze River basin

Identifiers

PMID40877851
PMCPMC12395641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.