Evidence map›Paper›PMID 40877820›Full record

Trial reportBMC pregnancy and childbirth2025

Effectiveness of a prenatal pilates program on ligamentous laxity and joint hypermobility in pregnant women: a dual-center randomized controlled trial.

Merve Bulguroglu, Halil Ibrahim Bulguroglu, Baran Degirmenci, Selcan Suicmez, Cansu Gevrek Aslan, Serenay Zorlu Develik, Nevin Atalay Guzel

Registry-linked trialAbstract readRandomized Controlled TrialMulticenter Study
In one paragraph

Trial report in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06684002 (Investigation of the Effect of Pilates Exercises on Laxity in Pregnant Women), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06684002 nacompletednot on this map

Investigation of the Effect of Pilates Exercises on Laxity in Pregnant Women

TypeinterventionalSponsorSelcan SuicmezRan2024 to 2025Enrolled42ConditionsPregnancy, Pilates Exercise, Laxity of LigamentArmsPilates training, Standard prenatal care and ergonomic advice
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Merve BulgurogluDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Ankara Medipol University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-5923-4720
Halil Ibrahim BulgurogluDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Ankara Medipol University, Ankara, Turkey. fztibrahim@hotmail.com.ORCID http://orcid.org/0000-0002-6767-7062
Baran DegirmenciDepartment of Family Medicine, Mugla Training and Research Hospital, Mugla, Turkey.ORCID http://orcid.org/0000-0002-5543-1487
Selcan SuicmezDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Ankara Medipol University, Ankara, Turkey.ORCID http://orcid.org/0009-0009-0354-8630
Cansu Gevrek AslanDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Ankara Medipol University, Ankara, Turkey.ORCID http://orcid.org/0000-0003-0750-3033
Serenay Zorlu DevelikDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Ankara Medipol University, Ankara, Turkey.ORCID http://orcid.org/0000-0002-3079-8688
Nevin Atalay GuzelDepartment of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Gazi University, Ankara, Turkey.ORCID http://orcid.org/0000-0003-0467-7310

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnancy-related anatomical and hormonal changes, including increased relaxin levels, may cause ligamentous laxity and joint hypermobility, while also contributing to decreased overall body mobility, potentially affecting functional stability. Pilates, focusing on core strength and postural control, is recommended during pregnancy, but its effects on ligamentous laxity and joint hypermobility have not been tested in a randomized controlled trial. This study aimed to investigate the effectiveness of a prenatal Pilates program on ligamentous laxity and joint hypermobility in pregnant women.

methodsIn this prospectively registered, dual-center randomized controlled trial (ClinicalTrials.gov: NCT06684002), 42 healthy primiparous women at 14-16 weeks' gestation were randomized to an 8-week structured prenatal Pilates program (n = 21) or standard prenatal care without exercise (n = 21). The intervention was delivered by the same certified physiotherapist at both centers to ensure consistency. Outcomes included anterior cruciate ligamentous laxity measured with the GNRB arthrometer, generalized joint hypermobility using the Beighton score, and activity limitations due to pelvic girdle pain assessed by the Pelvic Girdle Questionnaire, evaluated at baseline, 4 weeks, and 8 weeks.

resultsParticipants in the Pilates group showed no significant changes in ligamentous laxity and joint hypermobility and reported minimal activity limitations throughout the intervention (p > 0.05). In contrast, the control group demonstrated significant deterioration across all outcomes (p < 0.05). After 8 weeks, the Pilates group demonstrated significant improvements compared to the control group, with medium effect sizes for ligamentous laxity (p < 0.05, ηp² ≥ 0.06), a small effect size for joint hypermobility (p = 0.017, ηp² = 0.039), and a large effect size for activity limitations due to pelvic girdle pain (p = 0.021, ηp² = 0.317).

conclusionsAn 8-week structured prenatal Pilates program appears to effectively prevent the progression of ligamentous laxity and joint hypermobility while reducing activity limitations associated with pelvic girdle pain, supporting its integration into routine prenatal care to enhance maternal musculoskeletal stability, functional capacity, and quality of life during pregnancy.

trial registrationThis study is registered on ClinicalTrials.gov with the identifier NCT06684002, registration date November 9, 2024.

Indexed as

Exercise Movement TechniquesJoint InstabilityPregnancy ComplicationsPrenatal CareAdultFemaleHumansPelvic Girdle PainPregnancyProspective StudiesTreatment OutcomeYoung AdultJoint hypermobilityLigamentous laxityMaternal musculoskeletal healthPelvic girdle painPregnancyPrenatal pilatesQuality of lifeRandomized controlled trial

Identifiers

PMID40877820
PMCPMC12392537

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.