Evidence map›Paper›PMID 40877724›Full record

ArticleAnnals of surgical oncology2026

Breast Cancer Incidence Among Patients Undergoing Chest Masculinization Surgery: A Scoping Review.

Crystal Chu, Jennifer Goldman, Hyesong Joung, Sujeong Go, Randy Jones, John T Stranix

Abstract readScoping Review
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Crystal ChuUniversity of Virginia School of Nursing, Charlottesville, VA, USA. cdm9b@virginia.edu.ORCID http://orcid.org/0000-0002-4104-1920
Jennifer GoldmanDepartment of Plastic Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.
Hyesong JoungUniversity of Virginia School of Nursing, Charlottesville, VA, USA.
Sujeong GoUniversity of Virginia School of Nursing, Charlottesville, VA, USA.
Randy Jones *University of Virginia School of Nursing, Charlottesville, VA, USA.
John T Stranix *Department of Plastic Surgery, University of Virginia School of Medicine, Charlottesville, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe incidence of breast cancer (BC) cases among transgender males undergoing gender-affirming mastectomy (GAM) and the future BC risk for this population are not well established. This scoping review aimed to explore breast cancer incidence rates before and after GAM in the United States.

methodsFollowing the Arskey and O'Malley framework, the search was conducted in Embase and PubMed using keywords "gender-affirming surgery" and "breast cancer." The initial search resulted in 405 articles, with 36 articles imported to Covidence for the screening and selection phase. The articles were limited to the United States alone and within the last 10 years.

resultsFor final inclusion, 13 articles were identified (11 observational/retrospective cohort studies and 2 case studies). Across all the studies, 42 cases of atypia, 6 cases of ductal carcinoma in situ (DCIS), 1 case of Paget's disease, and 10 cases of invasive ductal carcinoma (IDC) were reported. Nine studies reviewed routine GAM surgical specimens (3869 cases), identifying 42 cases of atypia, 5 cases of DCIS, 1 case of Paget's disease, and 3 cases of IDC. Seven invasive carcinomas and one DCIS case were detected pre-GAM during screening and involved concurrent treatment from breast and plastic surgery teams.

conclusionsStandardization and best-practice screening protocols, including breast imaging before GAM and pathology performed on specimens collected during GAM, are needed. A shared decision-making approach and clinical coordination, including breast and plastic surgery for patients who receive a breast cancer diagnosis while pursuing GAM, can help achieve oncologic and cosmetic goals.

Indexed as

Breast NeoplasmsGender-Affirming SurgeryMastectomyTransgender PersonsFemaleHumansIncidenceMalePrognosisUnited StatesBreast cancerDecision aidDecisionKEYSScreeningShared decision making

Identifiers

PMID40877724
PMCPMC12689806

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.