ArticleBulletin of experimental biology and medicine2025
The Dynamics of Radiation-Induced Changes in Mice Behavior in the Marble Burying Test after Fractionated Gamma Irradiation.
Article in Bulletin of experimental biology and medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
We studied the effect of fractionated gamma irradiation at cumulative doses of 0.1, 1, and 5 Gy during the first month of life on the indices of anxious behavior in C57BL/6 mice in the early and delayed terms after the exposure. Anxiety was evaluated using the marble burying test. Persistent dose-dependent behavioral changes were revealed: irradiation at a dose of 0.1 Gy led to an increase in the anxiety level at the age of 1 and 6 months, whereas exposure at a dose of 5 Gy suppressed animal activity in the marble burying test until the age of 12 months. Irradiation at a dose of 1 Gy decreased anxiety parameters only in the delayed period after the irradiation.
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