Evidence map›Paper›PMID 40877538›Full record

ArticleScientific reports2025

A comparison of oral microbiome composition between highly trained competitive athletes and untrained controls.

Annabel Simpson, Bob T Rosier, Javier Pons Tamarit, Fiona Henriquez, Alex Mira, Chris Easton, Mia Burleigh

Abstract readComparative Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Annabel SimpsonSport and Physical Activity Research Institute, University of the West of Scotland, Blantyre, Scotland.
Bob T RosierDepartment of Health and Genomics, Centre for Advanced Research in Public Health, FISABIO Foundation, Valencia, Spain.
Javier Pons TamaritDepartment of Health and Genomics, Centre for Advanced Research in Public Health, FISABIO Foundation, Valencia, Spain.
Fiona HenriquezDepartment of Civil and Environmental Engineering, University of Strathclyde, Glasgow, Scotland.
Alex MiraDepartment of Health and Genomics, Centre for Advanced Research in Public Health, FISABIO Foundation, Valencia, Spain.
Chris EastonInstitute of Life and Earth Sciences, Heriot-Watt University, Edinburgh, UK.
Mia BurleighSport and Physical Activity Research Institute, University of the West of Scotland, Blantyre, Scotland. Mia.Burleigh@uws.ac.uk.

Funding

Hannah Research Foundation R57/S058CHA
6 · The paper itself

Abstract

The oral microbiome has a crucial role in nitric oxide (NO) production and contributes to oral and systemic health. This study compared oral microbiome composition and markers of NO production between highlytrained competitive athletes and inactive controls. Competitive athletes and untrained controls (N = 10 per group) were recruited. Saliva, plasma, supragingival plaque and the tongue dorsum microbiome were sampled. The microbiome was examined using long-read 16S rRNA sequencing and ozone-based chemiluminescence used to measure nitrate (NO

Indexed as

AthletesMicrobiotaMouthAdultBacteriaExerciseFemaleHumansMaleNitratesNitric OxideRNA, Ribosomal, 16SSalivaTongueYoung AdultNitratesNitric OxideRNA, Ribosomal, 16S16 s rRNADental diseaseExerciseExercise trainingNitrateNitrate-reductionNitric oxideNitrite-productionOral microbiomePhysical activity

Identifiers

PMID40877538
PMCPMC12394404

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.