Evidence map›Paper›PMID 40877423›Full record

ArticleJournal of neurology2025

Evaluating

Qi Zhang, Jiaying Lu, Luyao Wang, Fangyang Jiao, Min Wang, Kuangyu Shi, Chuantao Zuo, Jiehui Jiang, Alzheimer’s Disease Neuroimaging Initiative

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qi Zhang *School of Communication & Information Engineering, Shanghai University, No.99 Shangda Road, Baoshan District, Shanghai, 200444, China.
Jiaying Lu *Department of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, No.518 East Wuzhong Road, Xuhui District, Shanghai, 200235, China.
Luyao WangInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, No.99 Shangda Road, Baoshan District, Shanghai, 200444, China.
Fangyang JiaoDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, No.518 East Wuzhong Road, Xuhui District, Shanghai, 200235, China.
Min WangInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, No.99 Shangda Road, Baoshan District, Shanghai, 200444, China.
Kuangyu ShiDepartment of Nuclear Medicine, Bern University Hospital, University of Bern, Hochschulstrasse 6, 3012, Bern, Switzerland. kuangyu.shi@dbmr.unibe.ch.
Chuantao ZuoDepartment of Nuclear Medicine & PET Center, Huashan Hospital, Fudan University, No.518 East Wuzhong Road, Xuhui District, Shanghai, 200235, China. zuochuantao@fudan.edu.cn.
Jiehui JiangInstitute of Biomedical Engineering, School of Life Sciences, Shanghai University, No.99 Shangda Road, Baoshan District, Shanghai, 200444, China. jiangjiehui@shu.edu.cn.ORCID http://orcid.org/0000-0003-4948-3683
Alzheimer’s Disease Neuroimaging Initiative

Funding

National Natural Science Foundation of China 62206165National Natural Science Foundation of China 62376150National Natural Science Foundation of China 82020108013Science and Technology Innovation 2030 - Major Projects 2022ZD0211600
6 · The paper itself

Abstract

introductionTau protein aggregation is a hallmark of Alzheimer's disease (AD) pathology. Semi-quantitative analysis using regions of interest (ROIs)-based standardized uptake value ratios (SUVRs) serves as a major Tau positron emission tomography (PET) biomarker for AD diagnosis and staging. This study aims to evaluate the diagnostic performance of the second-generation tau tracer

methodsA total of 842 participants from two cohorts underwent tau PET imaging with either

results

conclusions

Indexed as

Alzheimer DiseaseCarbolinesCognitive DysfunctionPositron-Emission TomographyRadiopharmaceuticalstau ProteinsAgedAged, 80 and overCohort StudiesFemaleHumansMaleMiddle Aged7-(6-fluoropyridin-3-yl)-5H-pyrido(4,3-b)indoleCarbolinesRadiopharmaceuticalstau Proteins18F-Flortaucipir18F-FlorzolotauAlzheimer’s diseaseSemi-quantitative methodTau PET

Identifiers

PMID40877423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.