Evidence map›Paper›PMID 40877387›Full record

Observational studyScientific reports2025

Assessing the feasibility of HPV screening for cervical cancer in pregnant women in Ethiopia.

Selamawit Mekuria, Nahom Assiged, Habtamu Biazin, Christer Borgfeldt, Tamrat Abebe, Adane Mihret, Ola Forslund, Mats Jerkeman

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05125380 (Evaluation of an Human Papillomavirus), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05125380 naunknown statusnot on this map

Evaluation of an Human Papillomavirus (HPV) Based Screening Algorithm for Low and Middle Income Countries, by Self-sampling in Ethiopia

TypeinterventionalSponsorLund UniversityRan2021 to 2024Enrolled1,200ConditionsCervical Cancer, STI, Human Papilloma Virus, MicrobiotaArmsVIA (Visual Inspection with Acetic acid) and VILI (Visual Inspection with Lugol's Iodine), VIA (Visual Inspection with Acetic acid)
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Selamawit MekuriaDepartment of Medical Oncology, Lund University, 221 00, Lund, Sweden. selamawit.mekuria@med.lu.se.
Nahom AssigedArmauer Hansen Research Institiute, Addis Ababa, Ethiopia.
Habtamu BiazinArmauer Hansen Research Institiute, Addis Ababa, Ethiopia.
Christer BorgfeldtDepartment of Obstetrics and Gynecology, Linköping University, Linköping, Sweden.
Tamrat AbebeDepartment of Microbiology, Addis Ababa University, Addis Ababa, Ethiopia.
Adane MihretArmauer Hansen Research Institiute, Addis Ababa, Ethiopia.
Ola ForslundDepartment of Translational Medicine, Lund University, Malmö, Sweden.
Mats JerkemanDepartment of Medical Oncology, Lund University, 221 00, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnant women have historically and are currently being excluded from cervical cancer screening in most low and middle-income countries (LMICs). The aim of this study was to assess the feasibility and outcomes of including pregnant women in a HPV self-sampling-based screening program in Ethiopia. Pregnant women, recruited from a previously established cohort, were included. They answered a questionnaire and provided HPV self-samples. If the woman was HR-HPV positive, she underwent triage with VIA with or without Iodine. If positive in triage, the woman was re-scheduled after delivery for a new exam. Primary outcome was screening participation. The participation rate of pregnant women was 92.1% (117/127) (95% CI 86.0-96.1%). They had the same knowledge about cervical cancer and acceptance rate to the study as their non-pregnant peers. Pregnant women had less history of previous screening (p = 0.08). The HPV prevalence was 25.4% (29/114) in self-samples. 93.1% (27/29) attended follow-up, where only 11 had not delivered, and 54.6% (6/11) had detectable HPV infection in their cervical samples. Including pregnant women in HPV self-sampling-based screening is feasible and highly accepted. The findings support integrating pregnant women into cervical cancer screening programs in to enhance prevention and early detection efforts.Clinical trials ID: NCT05125380.

Indexed as

Early Detection of CancerPapillomaviridaePapillomavirus InfectionsUterine Cervical NeoplasmsAdultEthiopiaFeasibility StudiesFemaleHumansMass ScreeningPregnancySurveys and QuestionnairesYoung AdultCervical cancer screeningHPV self-samplingPregnancy

Identifiers

PMID40877387
PMCPMC12394452

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.