Evidence map›Paper›PMID 40877268›Full record

ArticleJournal of the American Chemical Society2025

An 18-Porphyrin Nanoring at the Size Limit for Global Aromaticity.

Jake M Holmes, Henrik Gotfredsen, Lene Gödde, Janko Hergenhahn, Kavita Rani, Keigo E Yamada, Jie-Ren Deng, Liv Warwick, Michael Clarke, Matthew Edmondson and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jake M HolmesDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.
Henrik GotfredsenDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.ORCID 0000-0002-9559-7190
Lene GöddeDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.
Janko HergenhahnDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.ORCID 0000-0002-1844-2734
Kavita RaniDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.
Keigo E YamadaDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.
Jie-Ren DengDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.
Liv WarwickSchool of Physics & Astronomy, University of Nottingham, Nottingham NG7 2RD, U.K.ORCID 0009-0001-1928-3018
Michael ClarkeSchool of Physics & Astronomy, University of Nottingham, Nottingham NG7 2RD, U.K.ORCID 0009-0003-4686-9801
Matthew EdmondsonSchool of Physics & Astronomy, University of Nottingham, Nottingham NG7 2RD, U.K.ORCID 0000-0002-8738-606X
James N O'SheaSchool of Physics & Astronomy, University of Nottingham, Nottingham NG7 2RD, U.K.
Alex SaywellSchool of Physics & Astronomy, University of Nottingham, Nottingham NG7 2RD, U.K.ORCID 0000-0002-2242-3149
Harry L AndersonDepartment of Chemistry, University of Oxford, Chemistry Research Laboratory, Oxford OX1 3TA, U.K.ORCID 0000-0002-1801-8132

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

What is the size limit for global aromaticity? How large can a macrocyclic π-system be and still exhibit an aromatic ring current around its circumference? We address this question by investigating a π-conjugated butadiyne-linked 18-porphyrin nanoring (diameter 8 nm). This nanoring was synthesized by two different strategies: classical template-directed synthesis, using a radial template with 18 pyridyl binding sites, and Vernier templating, using a small hexapyridyl template. Both strategies are effective when the porphyrins have octyloxy side chains, but classical templating is more effective than Vernier templating when the porphyrins have bulky trihexylsilyl substituents. The size and shape of the nanoring were confirmed by scanning tunneling microscopy.

Identifiers

PMID40877268
PMCPMC12426941

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.