Evidence map›Paper›PMID 40877187›Full record

SynthesisIn vivo (Athens, Greece)

Asbestos Exposure and Leukemia Incidence: A Systematic Review and Meta-analysis.

Konstantinos Dodos, Tsampika-Vasileia Kalamara, Petros Papalexis, Dimitrios Ap Keramydas, Effie G Papageorgiou, Vasiliki Epameinondas Georgakopoulou

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Konstantinos Dodos *Laboratory of Physiology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Tsampika-Vasileia Kalamara *Laboratory of Physiology, School of Medicine, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Petros Papalexis1st Department of Pathology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Dimitrios Ap Keramydas1st Department of Pathology, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Effie G PapageorgiouLaboratory of Reliability and Quality Control in Laboratory Hematology (HemQcR), Department of Biomedical Sciences, School of Health & Caring Sciences, University of West Attica, Athens, Greece; efipapag@uniwa.gr.
Vasiliki Epameinondas GeorgakopoulouDepartment of Pathophysiology, Laiko General Hospital, National and Kapodistrian University of Athens, Athens, Greece vaso_georgakopoulou@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimAsbestos comprises six naturally occurring fibrous minerals known for their health risks, particularly in occupational settings. This systematic review evaluates the association between asbestos exposure and leukemia incidence, synthesizing findings from various studies. MATERIALS AND

methodsWe conducted a comprehensive literature search in PubMed, Cochrane Library, and Web of Science, adhering to PRISMA guidelines. Studies included participants exposed to asbestos compared to matched controls, focusing on leukemia incidence. Data extraction and quality assessment were performed using the Newcastle-Ottawa Scale.

resultsA total of 1,751,580 participants were included, with 257,572 (14.7%) exposed to asbestos. The incidence of leukemia varied across studies, ranging from 0.02% to 0.45%. Meta-analysis revealed an overall risk ratio of 1.25 (95% confidence interval=0.81-1.94) with significant heterogeneity (I

conclusionThe findings highlight the complexity of the relationship between asbestos exposure and leukemia, influenced by factors such as exposure type, duration, and confounding variables like smoking. While some studies suggest a potential link, the evidence remains inconclusive, necessitating further research. This review underscores the need for high-quality studies to clarify the association between asbestos and leukemia, informing public health policies to reduce exposure risks and protect vulnerable populations.

Indexed as

AsbestosEnvironmental ExposureLeukemiaOccupational ExposureHumansIncidenceRisk FactorsAsbestosAsbestos-related diseasesenvironmental exposurehematopoietic neoplasmsleukemiaoccupational carcinogenesis

Identifiers

PMID40877187
PMCPMC12396040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.