ArticleIn vivo (Athens, Greece)
Cantharidin Suppresses Cell Viability and Induces Apoptosis of SK-N-SH and SH-SY5Y Cells.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimNeuroblastoma (NBL) is a pediatric malignancy with high mortality, particularly within the first year of life. Cantharidin, a natural terpenoid derived from blister beetles, has shown anticancer activity against several malignancies; however, its effect on NBL remains unexplored. In this study, we evaluated the antiproliferative and pro-apoptotic effects of cantharidin on SH-SY5Y and SK-N-SH NBL cell lines. MATERIALS AND
methodsThe cell viability and appearance of sub-G
resultsMTT assays revealed that treatment with 5 and 10 μM cantharidin for 24 and 48 h significantly reduced viability of both SH-SY5Y and SK-N-SH cells (all
conclusionThese findings support the hypothesis that cantharidin induces apoptosis
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.