Evidence map›Paper›PMID 40877176›Full record

ArticleIn vivo (Athens, Greece)

The Association of Insomnia and the Subsequent Cerebrovascular Accident in the Hypertension Population.

Ying-Chi Fan, Jing-Yang Huang, Chia-Yi Lee, Chao-Bin Yeh, Shih-Chi Su, Shun-Fa Yang

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ying-Chi FanInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Jing-Yang HuangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Chia-Yi LeeInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Chao-Bin YehSchool of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.
Shih-Chi SuWhole-Genome Research Core Laboratory of Human Diseases, Chang Gung Memorial Hospital, Keelung, Taiwan, R.O.C.; ssu1@cgmh.org.tw.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung, Taiwan, R.O.C.; ysf@csmu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimHypertension is a vascular condition associated with an increased risk of cerebrovascular accidents (CVAs). Insomnia has also been linked to various neurological disorders, including CVA. Therefore, this study aimed to investigate the potential association between insomnia and subsequent CVA development in a hypertensive population. PATIENTS AND

methodsA retrospective cohort study was conducted, enrolling patients with hypertension who were then categorized into groups based on the presence or absence of insomnia. Each group comprised 244,397 patients. The primary outcomes were the occurrences of CVAs, including both ischemic and hemorrhagic strokes. Cox proportional hazards regression analysis was used to calculate the adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for these outcomes to compare the insomnia and non-insomnia groups.

resultsThere were 22,608 ischemic strokes and 3,390 hemorrhagic strokes in the non-insomnia group, compared to 22,669 ischemic strokes and 3,484 hemorrhagic strokes in the insomnia group. The incidence of ischemic stroke (aHR=1.063; 95%CI=1.041-1.085;

conclusionIn individuals with hypertension, the presence of insomnia is associated with a significantly higher risk of both ischemic and hemorrhagic stroke.

Indexed as

HypertensionSleep Initiation and Maintenance DisordersStrokeAdultAgedFemaleHumansIncidenceIschemic StrokeMaleMiddle AgedProportional Hazards ModelsRetrospective StudiesRisk FactorsCerebrovascular accidenthemorrhage strokehypertensioninsomniaischemic stroke

Identifiers

PMID40877176
PMCPMC12396072

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.