Evidence map›Paper›PMID 40877165›Full record

ArticleIn vivo (Athens, Greece)

Impact of Polypharmacy on Perioperative Outcomes of Robot-assisted Laparoscopic Partial Nephrectomy for Small Renal Masses.

Yuki Nemoto, Hiroki Ishihara, Kazutaka Nakamura, Koichi Nishimura, Hironori Fukuda, Kazuhiko Yoshida, Junpei Iizuka, Tsunenori Kondo, Toshio Takagi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuki NemotoDepartment of Urology, Tokiwakai Jyoban Hospital, Fukushima, Japan.
Hiroki IshiharaDepartment of Urology, Tokyo Women's Medical University, Tokyo, Japan; ishihara.hiroki@twmu.ac.jp.
Kazutaka NakamuraDepartment of Urology, Tokyo Women's Medical University, Tokyo, Japan.
Koichi NishimuraDepartment of Urology, Tokyo Women's Medical University Adachi Medical Center, Tokyo, Japan.
Hironori FukudaDepartment of Urology, Tokyo Women's Medical University, Tokyo, Japan.
Kazuhiko YoshidaDepartment of Urology, Tokyo Women's Medical University, Tokyo, Japan.
Junpei IizukaDepartment of Urology, Tokyo Women's Medical University, Tokyo, Japan.
Tsunenori KondoDepartment of Urology, Tokyo Women's Medical University Adachi Medical Center, Tokyo, Japan.
Toshio TakagiDepartment of Urology, Tokyo Women's Medical University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimTo clarify the relationship between polypharmacy and perioperative outcomes in patients undergoing robot-assisted laparoscopic partial nephrectomy (RAPN) for small renal masses. PATIENTS AND

methodsThe clinical data of 2,392 patients who underwent RAPN for clinical T1 renal masses between January 2013 and November 2023 were retrospectively assessed. Polypharmacy was defined as patients taking five or more oral medications at the time of surgery. Perioperative outcomes were compared based on the polypharmacy status by balancing possible biases between the polypharmacy and non-polypharmacy groups using the propensity score matching (PSM) approach.

resultsOf 2,392 patients, 669 (28.0%) were classified into the polypharmacy group. After PSM, 532 non-polypharmacy patients were matched to the polypharmacy group. Patients in the polypharmacy group had a higher risk of perioperative complications (

conclusionPolypharmacy was significantly associated with inverse perioperative outcomes in patients who underwent RAPN for small renal masses. This can aid in determining optimal surgical indications and postoperative monitoring of RAPN.

Indexed as

Kidney NeoplasmsLaparoscopyNephrectomyPolypharmacyRobotic Surgical ProceduresAgedFemaleHumansLength of StayMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRetrospective StudiesTreatment OutcomeKidney cancerrenal cell carcinomaTrifecta

Identifiers

PMID40877165
PMCPMC12396044

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.