Evidence map›Paper›PMID 40877143›Full record

ArticleIn vivo (Athens, Greece)

Initial Experience With Proton Beam Therapy for Pancreatic Cancer at Shonan Kamakura General Hospital.

Shintaro Shiba, Sachika Shiraishi, Kazuya Koizumi, Yutaka Fujimoto, Naoto Ishiai, Koichi Tokuuye, Motoko Omura

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shintaro ShibaDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan; shiba48@gunma-u.ac.jp.
Sachika ShiraishiDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Kazuya KoizumiGastroenterology Medicine Center, Shonan Kamakura General Hospital, Kamakura, Japan.
Yutaka FujimotoDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Naoto IshiaiDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Koichi TokuuyeDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.
Motoko OmuraDepartment of Radiation Oncology, Shonan Kamakura General Hospital, Kamakura, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimIn Japan, proton beam therapy (PBT) for locally advanced pancreatic cancer was administered under an advanced medical treatment system until 2022; since then, it has been covered by national insurance. Our hospital initiated PBT for pancreatic cancer in July 2022. This study evaluated the clinical outcomes of PBT for pancreatic cancer after the initiation of national insurance coverage and assessed whether our initial experience at our hospital reproduced previously reported results. PATIENTS AND

methodsThis study included 10 patients with pancreatic cancer confirmed as inoperable due to locally advanced stage, comorbidity, or refusal to undergo surgery, without distant metastasis. All patients received a total PBT dose of 67.5 Gy (relative biological effectiveness) delivered in 25 fractions.

resultsThe median follow-up durations for all and surviving patients were 13.9 months (range=3.9-24.6 months) and 19.5 months (range=8.1-24.6 months), respectively. The 1- and 2-year overall survival and local control rates were 70% and 35%, and 89% and 89%, respectively. No grade 3 or higher acute or late non-hematological toxicities associated with PBT were observed.

conclusionThe clinical outcomes at the newly established PBT facility were comparable and reproducible to those observed in patients treated under the previous advanced medical treatment system.

Indexed as

Pancreatic NeoplasmsProton TherapyAgedAged, 80 and overFemaleHospitals, GeneralHumansJapanMaleMiddle AgedNeoplasm StagingTreatment OutcomePancreatic cancerproton beam therapyradiotherapy

Identifiers

PMID40877143
PMCPMC12396055

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.