Trial reportBMJ open2025
Effect of perioperative music on delirium after hip fracture operations (MCHOPIN): a multicentre randomised clinical trial in Dutch hospitals.
Trial report in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- The Impact of Recorded Music on Postoperative Delirium in Older Adults After Hip Fracture Surgery (IPOD): A Quasi-Experimental Study.Journal of the American Geriatrics Society · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPostoperative delirium is a frequent complication with possible detrimental consequences in older hip fracture patients. Music interventions are promising, with positive effects on risk factors for delirium. This study aimed to assess the impact of perioperative music on postoperative delirium in older hip fracture patients.
designProspective randomised controlled trial.
settingMulticentre study, performed in six participating hospitals in the Netherlands.
participantsEligibility criteria included patients aged ≥65 years with an acute hip fracture requiring surgery and documented informed consent. 449 patients were randomised, with a median age of 81 years (IQR 74-87), including 287 women (63.9%).
interventionsMusic group participants received the intervention preoperatively, intraoperatively, and postoperatively twice a day for 30 min. The control group received standard-of-care, supplemented by headphones without music intraoperatively for equal noise reduction in both groups. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome was delirium diagnosis (Diagnostic and Statistical Manual of Mental Disorders, fifth edition), assessed by a geriatrician. Associations were analysed using regression models. Secondary outcomes included: Delirium Observational Score, anxiety, pain and postoperative complications.
resultsIntention-to-treat analysis showed no statistically significant decrease of delirium in the music group, compared with the control group (OR 0.685 (95% CI 0.378 to 1.242); p=0.21). However, in the modified-intention-to-treat analysis, a significant decrease in postoperative delirium was observed (OR 0.478 (95% CI 0.245 to 0.933); p=0.028), which is substantiated by a logistic regression (OR 0.43 (95 % CI 0.19 to 0.98); p=0.045). Also, more postoperative complications were observed in the control group (93 (43.3%); 66 (32.7); p=0.026) in this analysis. The intervention was associated with high patient satisfaction and no adverse events.
conclusionsThis study suggests a positive effect of music interventions on postoperative delirium, which provides additional evidence for considering the implementation of these interventions in hip fracture care. TRIAL REGISTRATION NUMBER: International Clinical Trial Registry Platform, Dutch Trial Register (www.onderzoekmetmensen.nl/, ID:NTR7036).
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