Evidence map›Paper›PMID 40876876›Full record

ArticleBMJ open2025

Impact of cardiac rehabilitation exercise management on improving exercise tolerance among patients with chronic heart disease using a telemetry-based biosignal measurement device: protocol for a multicentre randomised controlled trial in Japan (iCARE-MATE study).

Junya Yamagishi, Takatomo Watanabe, Jun Matsumoto-Miyazaki, Yuki Sahashi, Daichi Watanabe, Ryuta Asada, Hiroyuki Okura

Abstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junya Yamagishi *Department of Rehabilitation, Gifu University Hospital, Gifu, Japan.
Takatomo Watanabe *Department of Cardiology, Gifu University Graduate School of Medicine, Gifu, Japan watanabe.takatomo.n6@f.gifu-u.ac.jp.ORCID http://orcid.org/0000-0003-4111-5819
Jun Matsumoto-MiyazakiDepartment of Cardiology, Gifu University Graduate School of Medicine, Gifu, Japan.ORCID http://orcid.org/0000-0003-0303-5017
Yuki SahashiDepartment of Cardiology, Gifu University Graduate School of Medicine, Gifu, Japan.
Daichi WatanabeInnovative and Clinical Research Promotion Center, Gifu University Hospital, Gifu, Japan.
Ryuta AsadaInnovative and Clinical Research Promotion Center, Gifu University Hospital, Gifu, Japan.
Hiroyuki OkuraDepartment of Cardiology, Gifu University Graduate School of Medicine, Gifu, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionCardiac rehabilitation (CR) improves the outcomes of patients with chronic heart disease. However, participation in hospital-based programs is limited, partly because of accessibility issues. Notably, most CRs are performed unsupervised at home, making it challenging for healthcare providers and patients to monitor progress accurately or provide tailored feedback. Wearable devices are increasingly used to track physical activity; however, many require smartphone operations, which can be difficult for older adults. The purpose of this study is to evaluate whether a simple telemetry system for activity tracking and feedback could improve exercise tolerance in outpatients with chronic heart disease undergoing unsupervised CR at home. METHODS AND ANALYSIS: This open-label, multicentre, randomised controlled trial will include 140 patients with cardiovascular diseases aged ≥20 years with percent of peak oxygen uptake (%peak VO2) <80%. Eligible patients will undergo a 2-4-week observation period followed by cardiopulmonary exercise testing. Participants with <3% peak VO2 change over 6 months will be randomised in a 1:1 ratio to either the intervention (device) or control (no device) group. The intervention group will use a wearable device to track daily activities and receive exercise guidance based on these data every 4 weeks. The control group will not use the device or receive feedback. The primary outcome is the 12-week change in peak VO ETHICS AND DISSEMINATION: This study was designed in accordance with the principles of the Declaration of Helsinki. Gifu University Graduate School of Medicine Ethics Committee approved this study (approval number: 2022-081), and all participants will sign an informed consent form.

trial registrationThis study has been registered at the Japan Registry of Clinical Trials (jRCT; registration number, 1042220058; URL, https://jrct.mhlw.go.jp/en-latest-detail/jRCT1042220058; date of registration, 26 August 2022).

Indexed as

Cardiac RehabilitationExercise TherapyExercise ToleranceHeart DiseasesTelemetryAdultAgedChronic DiseaseFemaleHumansJapanMaleMiddle AgedMulticenter Studies as TopicRandomized Controlled Trials as TopicWearable Electronic DevicesCardiovascular DiseaseExerciseREHABILITATION MEDICINEWearable Devices

Identifiers

PMID40876876
PMCPMC12410617

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.