Evidence map›Paper›PMID 40876704›Full record

ReviewCannabis and cannabinoid research2026

Age-Related Effects of Cannabis and Cannabinoids on Brain and Behavior.

Conor H Murray, Joshua Cassarino, Ziva D Cooper

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cannabis and cannabinoid research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Conor H MurrayDepartment of Psychiatry and Biobehavioral Sciences, UCLA Center for Cannabis and Cannabinoids, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-9954-7601
Joshua CassarinoDepartment of Psychiatry and Biobehavioral Sciences, UCLA Center for Cannabis and Cannabinoids, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.
Ziva D CooperDepartment of Psychiatry and Biobehavioral Sciences, UCLA Center for Cannabis and Cannabinoids, Jane and Terry Semel Institute for Neuroscience and Human Behavior, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California, USA.ORCID 0000-0001-8001-2332

Funding

Sex-dependent effects of cannabis: Assessing abuse-related and pharmacokinetic differences between men and womenR01DA047296 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI COOPER, ZIVA D · 2019 to 2024
$3.5M
Age-and sex-dependent pharmacodynamics and pharmacokinetics of oral and smoked delta-9-THCR01DA057252 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZIVA D COOPER · 2022 to 2026
$2.6M
NIDA NIH HHS R01 DA047296NIDA NIH HHS R01 DA057252
6 · The paper itself

Abstract

introductionThe effect of cannabis use on health is likely to depend on individual differences. In particular, there is a growing need to understand the impact of cannabis and delta-9-tetrahydrocannabinol (THC) on brain and behavioral health across the lifespan. MATERIALS AND

methodsWe conducted a narrative review summarizing the effects of cannabis and THC across three stages of life:

resultsRecent epidemiological data indicate a potential reversal of both the escalating rates of cannabis use and low perceptions of risk among pregnant women and adolescents. Findings across preclinical and clinical studies support high perceptions of risk for individuals

conclusionsOur findings emphasize the necessity for clinical and policy recommendations to mitigate the risks associated with cannabis use and to enhance public understanding of its implications on neurodevelopmental and psychiatric disorders. Continued research and educational strategies are essential to address these evolving trends and reduce harm.

Indexed as

BrainCannabinoidsCannabisDronabinolAdolescentAdultAge FactorsFemaleHumansPregnancyYoung AdultCannabinoidsDronabinolagebraincannabiscognitionlifetimemood

Identifiers

PMID40876704
PMCPMC13157645

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.