ArticlePloS one2025
Knee arthroplasty can preserve cognitive function in patients with severe knee osteoarthritis.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Impact of cognitive impairment on postoperative delirium and discharge disposition following knee arthroplasty: a Japanese nationwide propensity score-matched study.Archives of orthopaedic and trauma surgery · 2026Article
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6 authors.
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Abstract
backgroundThis study examined how the clinical and radiological severity of knee osteoarthritis (OA) and various treatment methods affect cognitive function.
methodThis prospective study included patients with knee pain or discomfort who visited a single institution between July 2017 and November 2022. Patients with Kellgren-Lawrence (K-L) grade 0 or treatable dementia were excluded from this study, and 88 patients were followed up for an average duration of 2.4 ± 1.3 years. Overall, 55 patients had K-L grade 4, of whom 45 who did not improve after >3 months of conservative treatment underwent knee arthroplasty.
resultsAmong patients with K-L grade 4, the decrease in the Mini-Mental State Examination score in patients who underwent surgery was significantly lower than that in other patients who received conservative treatment only.
conclusionKnee arthroplasty can reduce the decline in cognitive function in patients with severe knee OA of K-L grade 4 who do not respond to conservative treatment. Even if pain is controlled with conservative treatment, the decline in cognitive function in patients with OA is faster than the age-related decline observed in the general population.
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