Evidence map›Paper›PMID 40875496›Full record

ArticleMMWR. Morbidity and mortality weekly report2025

Drug Overdose Deaths Involving Stimulants - United States, January 2018-June 2024.

Lauren J Tanz, Kimberly D Miller, Amanda T Dinwiddie, R Matt Gladden, Alice Asher, Grant Baldwin, Brandon Nesbit, Julie O'Donnell

Abstract read
In one paragraph

Article in MMWR. Morbidity and mortality weekly report, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lauren J TanzDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.
Kimberly D MillerDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.
Amanda T DinwiddieDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.
R Matt GladdenDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.
Alice AsherDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.
Grant BaldwinDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.
Brandon NesbitDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.
Julie O'DonnellDivision of Overdose Prevention, National Center for Injury Prevention and Control, CDC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug overdose deaths involving stimulants have increased in the United States since 2011. This report describes characteristics of stimulant-involved overdose deaths during January 2021-June 2024 using CDC's State Unintentional Drug Overdose Reporting System data and trends by drug and race and ethnicity during 2018-2023 using CDC's National Vital Statistics System data. Overall, 59.0% of overdose deaths involved stimulants, 43.1% co-involved stimulants and opioids, and 15.9% involved stimulants and no opioids during January 2021-June 2024. Persons who died of overdoses involving stimulants and no opioids were older (aged ≥45 years; 66.5% versus 44.2%) and more frequently had a history of cardiovascular disease (38.7% versus 21.2%) than those who died of overdoses involving stimulants and opioids. Stimulant-involved overdose death rates increased from 2018 to 2023 (cocaine: 4.5 per 100,000 population to 8.6; psychostimulants with abuse potential, primarily methamphetamine: 3.9 to 10.4). Increases were largest for psychostimulants among non-Hispanic American Indian or Alaska Native persons (11.0 in 2018 to 32.9 in 2023) and cocaine among non-Hispanic Black or African American persons (9.1 to 24.3), driven by deaths co-involving stimulants and opioids. Increases in stimulant-involved deaths suggest the need for expanded access to evidence-based stimulant use disorder treatments, evaluation of medication-based treatments for stimulant use disorder and treatments for co-occurring substance use disorders, and engagement of persons who use stimulants and who might be missed by opioid-focused prevention efforts.

Indexed as

Central Nervous System StimulantsDrug OverdoseAdolescentAdultAgedAnalgesics, OpioidEthnicityFemaleHumansMaleMiddle AgedUnited StatesYoung AdultAnalgesics, OpioidCentral Nervous System Stimulants

Identifiers

PMID40875496
PMCPMC12393691

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.