ArticleRadiation protection dosimetry2025
Development of a method for evaluation of absorbed doses in preclinical in vivo μCT.
Article in Radiation protection dosimetry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A pilot longitudinal spectral CT study of fructose-related bone microstructure in rats: exploring technical advantages.Frontiers in physiology · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
In vivo preclinical X-ray micro-computed tomography (μCT) imaging is widely used to obtain three-dimensional anatomical information of small animals. However, the potential for radiation exposure to influence experimental outcomes necessitates accurate dose estimation. The aim of this study was to develop a robust and reproducible method for estimating and evaluating absorbed doses in small animals undergoing preclinical in vivo μCT imaging. Absorbed doses were measured at four separate positions within a dedicated polymethyl methacrylate phantom using MCP-N (LiF, Cu, P) thermoluminescence dosemeters (TLDs) and a novel type of optically stimulated luminescence dosemeter (OSLD) made from household salt (NaCl). The findings were benchmarked against the vendor's absorbed dose estimates, revealing a discrepancy between the measured and provided values. The results for the OSLDs followed a similar trend to the TLDs, though significant statistical differences were found between the luminescent dosemeters and the vendor values. In this study, a method for measuring the absorbed doses from μCT systems was presented. The results indicate a need for thorough dose measurements prior to performing longitudinal imaging studies.
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Registered trials
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