Evidence map›Paper›PMID 40875251›Full record

ArticleThe FEBS journal2026

Biostimulants in plant brassinosteroid hormone receptor BRI1 activation-a new system to evaluate activation capacity.

Maribel Marquina, Montserrat Ricart-Fort, Rocío Díaz-Parra, Sandra López-Avilés, Tula Yance, Pablo Quirós, Elena Contreras, Ignasi Salaet, Sergio Atares, Rosa Aligué

Abstract read
In one paragraph

Article in The FEBS journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Maribel MarquinaDepartment of Biomedical Science, University of Barcelona, Spain.
Montserrat Ricart-FortDepartment of Biomedical Science, University of Barcelona, Spain.
Rocío Díaz-ParraDepartment of Biomedical Science, University of Barcelona, Spain.
Sandra López-AvilésDepartment of Biosciences, Faculty of Mathematics and Natural Sciences, University of Oslo, Norway.
Tula YanceDepartamento de I+D+i de Fertinagro Biotech S.L, Poligono Industrial La Paz, Teruel, Spain.
Pablo QuirósDepartamento de I+D+i de Fertinagro Biotech S.L, Poligono Industrial La Paz, Teruel, Spain.
Elena ContrerasDepartamento de I+D+i de Fertinagro Biotech S.L, Poligono Industrial La Paz, Teruel, Spain.
Ignasi SalaetDepartamento de I+D+i de Fertinagro Biotech S.L, Poligono Industrial La Paz, Teruel, Spain.
Sergio AtaresDepartamento de I+D+i de Fertinagro Biotech S.L, Poligono Industrial La Paz, Teruel, Spain.
Rosa AliguéDepartment of Biomedical Science, University of Barcelona, Spain.ORCID 0000-0002-2085-325X

Funding

Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya 10005ITDepartament d'Innovació, Universitats i Empresa, Generalitat de Catalunya 2021 SGR 00007Ministerio de Ciencia y Tecnología RTC2019-006922-2
6 · The paper itself

Abstract

The search for innovative and alternative chemical methods to manage plant growth is an ever-increasing reality. Biostimulants, products of biological origin, have shown promise in improving various agronomic characteristics and boosting yield. However, the selection and characterization of biostimulant matrices is a complex process that requires rigorous evaluation adapted to the specific needs of each plant. Because mixtures of biologically active compounds are present in biostimulants, efficient methods are required to characterize their potential mode of action. In this study, a new approach was developed to assess the biological activity of biostimulants by activating specific plant receptors involved in key physiological processes. It is based on the heterologous expression in fission yeast of brassinosteroid receptor protein Brassinosteroid Insensitive 1 (BRI1), which is involved in plant growth and development, and its specific activation by brassinolide (BL). The method involves the identification of highly expressed genes in response to BL activation of the BRI1 receptor, to generate a GFP reporter gene system that is switched on when biostimulants activate the BRI1 receptor. The biostimulants selected for testing were hydrolysates of animal origin. The results not only revealed variations in BRI1 activation among biostimulants, but also highlighted that samples from the same origin exhibit different BRI1 activation capacities depending on their processing methods. This new method enables direct classification of the mode of action of biostimulants by assessing their ability to activate specific plant receptors, providing a valuable resource for biostimulant research and development.

Indexed as

ArabidopsisArabidopsis ProteinsBrassinosteroidsPlant Growth RegulatorsProtein KinasesSteroids, HeterocyclicGene Expression Regulation, PlantGenes, ReporterGreen Fluorescent ProteinsArabidopsis ProteinsbrassinolideBrassinosteroidsBRI1 protein, ArabidopsisGreen Fluorescent ProteinsPlant Growth RegulatorsProtein KinasesSteroids, Heterocyclicbioactive natural productsbiostimulantsbrassinolidebrassinosteroids receptorsfission yeastsustainable agriculture

Identifiers

PMID40875251
PMCPMC12871906

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.