Evidence map›Paper›PMID 40875127›Full record

ReviewJournal of gastrointestinal cancer2025

Primary Intrahepatic Biliary Neuroendocrine Neoplasms: A Case Report and Literature Review.

Zhengfu Chen, Lifu Hu, Zixian Guo, Jingxiang Chu, Tao He, Changyong E, Tao Jiang

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Journal of gastrointestinal cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhengfu ChenJilin University, Changchun, China.
Lifu HuThe Third Bethune Hospital of Jilin University, Changchun, Jilin, China.
Zixian GuoJilin University, Changchun, China.
Jingxiang ChuJilin University, Changchun, China.
Tao HeJilin University, Changchun, China.
Changyong EThe Third Bethune Hospital of Jilin University, Changchun, Jilin, China. Echangyong@jlu.edu.cn.
Tao JiangThe Third Bethune Hospital of Jilin University, Changchun, Jilin, China. Jiangtao99@jlu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIntrahepatic biliary neuroendocrine neoplasms (NENs) are rare neoplasms originating from neuroendocrine cells in the intrahepatic bile ducts. Patients often present without hormone-related symptoms but are admitted due to jaundice or abdominal pain. PRESENTATION OF CASE: This case report describes a 57-year-old female patient who experienced intermittent upper abdominal pain for one month prior to admission. A computed tomography (CT) scan at a local hospital revealed an intrahepatic space-occupying lesion. Magnetic Resonance Cholangiopancreatography (MRCP) at our hospital identified a mass at the root of the left hepatic duct, accompanied by secondary dilation of the left intrahepatic bile ducts. Liver function tests and tumor markers were within normal ranges, and no jaundice or metastatic signs were observed. The patient underwent robot-assisted left hemihepatectomy and cholecystectomy, with a smooth postoperative recovery. Pathological examination confirmed a neuroendocrine tumor (NET G2), measuring 2.2×2×1.6 cm. Postoperative positron emission tomography / computedtomography (PET/CT) scans detected no tumors elsewhere, confirming the intrahepatic bile duct as the primary site.

conclusionBiliary NENs are exceedingly rare and challenging to diagnose preoperatively. Surgical resection remains the most effective treatment for achieving cure or prolonging survival.

Indexed as

Bile Duct NeoplasmsBile Ducts, IntrahepaticNeuroendocrine TumorsCholangiopancreatography, Magnetic ResonanceCholecystectomyFemaleHepatectomyHumansMiddle AgedPositron Emission Tomography Computed TomographyCase reportIntrahepatic biliaryNeuroendocrine neoplasms

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.