Evidence map›Paper›PMID 40875103›Full record

ReviewNetherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation2025

Anticoagulation and thromboembolic risk in critically ill patients with trigger-induced atrial fibrillation-A systematic review and meta-analysis.

Jasper Koolwijk, Mileen van de Kar, Brittney A van der Woude, Marcel van 't Veer, Harm Jan de Grooth, Harry J G M Crijns, Lukas R C Dekker, R Arthur Bouwman, Olaf L Cremer, Ashley J R de Bie and 1 more

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In one paragraph

Review in Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Jasper KoolwijkDepartment of Anesthesiology, Intensive Care and Pain Medicine, Catharina Hospital Eindhoven, Eindhoven, The Netherlands. jasper.koolwijk@catharinaziekenhuis.nl.ORCID http://orcid.org/0000-0003-0763-5693
Mileen van de KarDepartment of Cardiology and Cardiothoracic Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Brittney A van der WoudeIntensive Care Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Marcel van 't VeerDepartment of Cardiology and Cardiothoracic Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Harm Jan de GroothIntensive Care Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Harry J G M CrijnsDepartment of Cardiology, Maastricht University Medical Center, Cardiovascular Research Institute Maastricht, Maastricht, The Netherlands.
Lukas R C DekkerDepartment of Cardiology and Cardiothoracic Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
R Arthur BouwmanDepartment of Anesthesiology, Intensive Care and Pain Medicine, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Olaf L CremerIntensive Care Center, University Medical Center Utrecht, Utrecht, The Netherlands.
Ashley J R de BieDepartment of Intensive Care, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.
Luuk C OtterspoorDepartment of Cardiology and Cardiothoracic Surgery, Catharina Hospital Eindhoven, Eindhoven, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn critically ill patients with trigger-induced atrial fibrillation, there are no definitive recommendations on the use of anticoagulation. This study aimed to evaluate the association between anticoagulation therapy and outcomes (i.e. thromboembolism, bleeding and mortality) and examine prescription patterns in high-risk individuals based on CHA

methodsA systematic search was conducted to identify studies reporting on anticoagulation prescription, thromboembolism, bleeding, and mortality. Anticoagulation rates and CHA

resultsAnticoagulation prescription rates ranged from 3 to 86%; in over 50% of patients, CHA

conclusionThe prescription of anticoagulation in critically ill patients with TIAF is highly variable. There is no clear evidence of benefit or harm, and neither routine use nor systematic omission is supported.

Indexed as

AnticoagulationAtrial fibrillationBleedingCritical illnessIntensive careSepsisStrokeThromboembolism

Identifiers

PMID40875103
PMCPMC12454756

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.