Evidence map›Paper›PMID 40874995›Full record

ArticleHerzschrittmachertherapie & Elektrophysiologie2026

Cardioinhibitory reflex syncope : Cardioneuroablation as a therapeutic alternative.

Amelie Beblo, Robert Hättasch, Nikolaos Dagres, Felix Hohendanner, Gerhard Hindricks, Sergio Richter, Verena Tscholl

Abstract readCase Reports
PubMed Publisher
In one paragraph

Article in Herzschrittmachertherapie & Elektrophysiologie, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amelie BebloKlinik für Kardiologie, Angiologie und Intensivmedizin, Campus Mitte, Deutsches Herzzentrum der Charité, Charitéplatz 1, 10117, Berlin, Germany. amelie.beblo@dhzc-charite.de.
Robert HättaschKlinik für Kardiologie, Angiologie und Intensivmedizin, Campus Mitte, Deutsches Herzzentrum der Charité, Charitéplatz 1, 10117, Berlin, Germany.
Nikolaos DagresKlinik für Kardiologie, Angiologie und Intensivmedizin, Campus Mitte, Deutsches Herzzentrum der Charité, Charitéplatz 1, 10117, Berlin, Germany.
Felix HohendannerKlinik für Kardiologie, Angiologie und Intensivmedizin, Campus Mitte, Deutsches Herzzentrum der Charité, Charitéplatz 1, 10117, Berlin, Germany.
Gerhard HindricksKlinik für Kardiologie, Angiologie und Intensivmedizin, Campus Mitte, Deutsches Herzzentrum der Charité, Charitéplatz 1, 10117, Berlin, Germany.
Sergio RichterHerzzentrum Dresden, Klinik für Innere Medizin und Kardiologie, Universitätsklinik, Technische Universität Dresden, Fetscherstraße 76, 01307, Dresden, Germany.
Verena TschollKlinik für Kardiologie, Angiologie und Intensivmedizin, Campus Mitte, Deutsches Herzzentrum der Charité, Charitéplatz 1, 10117, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The case of a 36-year-old female patient with recurrent reflex syncope characterized by predominant cardioinhibition and episodes of asystole lasting up to 9 s, as documented by an implantable loop recorder, is reported. Given her young age and symptomatic burden, cardioneuroablation (CNA) was performed without complications as an alternative to pacemaker implantation, in accordance with European Heart Rhythm Association (EHRA) recommendations. In this case, CNA has shown to be an effective and safe treatment option for managing recurrent cardioinhibitory reflex syncope. CNA should particularly be considered and offered in specialised centres for symptomatic patients under 40 years of age, in which treatment options beyond conservative measures remain limited.

Indexed as

Catheter AblationSyncopeSyncope, VasovagalAdultFemaleHumansTreatment OutcomeCardioinhibitionElectrophysiological studyEvent recorderParasympathetic gangliaVagal denervation

Identifiers

PMID40874995

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.