Evidence map›Paper›PMID 40874958›Full record

ArticleAntonie van Leeuwenhoek2025

Bioprotective potential of biosynthesized copper oxide nanoparticles and copper phosphite against Alternaria-solani-induced leaf spot in pepper plants.

Mohamed S Attia, Mohamed H Moustafa, Amr H Hashem, Salah M Elsayed, Abeer S Aloufi, Ismail Mostafa Ismail Abdelaleem, Karim A Alshahed, Abdelrhman S Ismail, Abdelrhman M Ibrahim, Mostafa A Abdel-Maksoud and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Antonie van Leeuwenhoek, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mohamed S AttiaBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.
Mohamed H MoustafaCollege of Pharmacy, Al-Farahidi University, Baghdad, Iraq.
Amr H HashemBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt. amr.hosny86@azhar.edu.eg.
Salah M ElsayedHorticulture Research Institute, Agricultural Research Center, Giza, Egypt.
Abeer S AloufiDepartment of Biology, College of Science, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, 11671, Riyadh, Saudi Arabia.
Ismail Mostafa Ismail AbdelaleemBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.
Karim A AlshahedBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.
Abdelrhman S IsmailBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.
Abdelrhman M IbrahimBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt.
Mostafa A Abdel-MaksoudBotany and Microbiology Department, College of Science, King Saud University, Riyadh, Saudi Arabia.
Abdulaziz AlamriBiochemistry Department-College of Science, King Saud University, Riyadh, Saudi Arabia.
Hossam EbaidDepartment of Zoology, College of Science, King Saud University, P.O. Box 2455, 11451, Riyadh, Saudi Arabia.
Bushra Hafeez KianiDepartment of Biology and Biotechnology, Worcester Polytechnic Institute, Worcester, MA, 01609, USA.
Hanan El BakkaliMafa Bioscience-Spain, Granada, Spain.
Amer M AbdelazizBotany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City, Cairo, 11884, Egypt. amermorsy@azhar.edu.eg.

Funding

Princess Nourah Bint Abdulrahman University PNURSP2025R357
6 · The paper itself

Abstract

Alternaria solani leaf spot disease (ASLS) poses a serious threat to global crop production, including peppers, resulting in notable economic losses. Bio-nanotechnology offers promising solutions for combating plant pathogens by promoting plant defenses and inhibiting pathogen growth. This study explores the effectiveness of copper oxide nanoparticles (CNPs) and copper phosphite (MAXIFOS CU®) in controlling A. solani and boosting growth and defense responses in pepper plants. CNPs were biosynthesized using Penicillium expansum first time and thoroughly characterized through various techniques. Analysis confirmed that the nanoparticles varied in shape, predominantly oval and spherical, with an average size of approximately 40.59 nm, as shown in HR-TEM images. DLS analysis indicated a mean particle size of 74.58 nm, and Zeta potential analysis at pH 7.2 revealed a negative surface charge of - 55.25 mV, attributed to the components of the fungal extract. The study demonstrated that both CNPs and MAXIFOS CU® exhibited antifungal activity against A. solani, with CNPs effectively reducing PDI by 27.5% and enhancing overall plant protection by 65.62%. Results indicated that treated plants showed improvements in photosynthetic pigments, proline content (MAXIFOS CU® 28 g/L increase by 108.3%, while CNPs 81.30%), total phenolic compounds (CNPs 80.70% increase, while MAXIFOS CU® a 68.70%), H

Indexed as

AlternariaCapsicumCopperMetal NanoparticlesNanoparticlesPhosphitesPlant DiseasesAntifungal AgentsPenicilliumPlant LeavesAntifungal AgentsCoppercupric oxidecuprous oxidePhosphitesAlternaria solaniBiocontrolCuO-NPsMaxifos Cu®MycosynthesizedPepper

Identifiers

PMID40874958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.