Evidence map›Paper›PMID 40874838›Full record

ArticleRadiology. Cardiothoracic imaging2025

Improved Myocardial Tissue Characterization Using Delayed-Phase Dynamic Contrast-enhanced Cardiac MRI.

Li-Ting Huang, Xinheng Zhang, Xinqi Li, Archana Malagi, Yuheng Huang, Xingmin Guan, Hao Ho, Alan Kwan, Janet Wei, Xiaoming Bi and 6 more

Abstract read
In one paragraph

Article in Radiology. Cardiothoracic imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Li-Ting HuangDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, 8700 Beverly Blvd, PACT, Ste 400, Los Angeles, CA 90048.ORCID 0000-0001-5616-0431
Xinheng ZhangKrannert Cardiovascular Research Center, Indiana University, Bloomington, Ind.ORCID 0000-0002-6347-8066
Xinqi LiDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, 8700 Beverly Blvd, PACT, Ste 400, Los Angeles, CA 90048.ORCID 0009-0002-4799-8333
Archana MalagiDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, 8700 Beverly Blvd, PACT, Ste 400, Los Angeles, CA 90048.ORCID 0000-0002-2332-170X
Yuheng HuangKrannert Cardiovascular Research Center, Indiana University, Bloomington, Ind.ORCID 0009-0000-2890-2442
Xingmin GuanKrannert Cardiovascular Research Center, Indiana University, Bloomington, Ind.ORCID 0000-0002-3698-1811
Hao HoDepartment of Statistics, University of California at Los Angeles, Los Angeles, Calif.
Alan KwanHeart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.ORCID 0000-0002-4393-1011
Janet WeiHeart Institute, Cedars-Sinai Medical Center, Los Angeles, Calif.ORCID 0000-0002-1311-618X
Xiaoming BiSiemens Medical Solutions USA, Los Angeles, Calif.ORCID 0000-0001-6286-9172
Anthony G ChristodoulouDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, 8700 Beverly Blvd, PACT, Ste 400, Los Angeles, CA 90048.ORCID 0000-0002-9334-8684
Debiao LiDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, 8700 Beverly Blvd, PACT, Ste 400, Los Angeles, CA 90048.ORCID 0000-0001-8560-8231
Hui HanDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, 8700 Beverly Blvd, PACT, Ste 400, Los Angeles, CA 90048.ORCID 0000-0003-4440-4421
Yen-Wen LiuDepartment of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.ORCID 0000-0003-4662-628X
Rohan DharmakumarKrannert Cardiovascular Research Center, Indiana University, Bloomington, Ind.
Hsin-Jung YangDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Biomedical Imaging Research Institute, 8700 Beverly Blvd, PACT, Ste 400, Los Angeles, CA 90048.ORCID 0000-0001-9379-5495

Funding

Expanding on a new paradigm for MRI in pediatric congenital heart diseaseR01HL127153 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHRISTODOULOU, ANTHONY G, FINN, JOHN PAUL · 2015 to 2024
$6.1M
Developing a MRI-guided Disease-Modifying Therapy for Post Infarction Chronic Heart FailureR01HL133407 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI Rohan Dharmakumar · 2017 to 2026
$4.9M
Push-Button Cardiac MRI for Non-Invasive Quantification of Myocardial Energy Consumption in Heart FailureR01HL165211 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Hsin-Jung Yang · 2022 to 2026
$3.9M
Women's Ischemia Syndrome Evaluation (WISE) - Mechanisms of Coronary Microvascular Dysfunction Leading to Pre-Heart Failure with Preserved Ejection Fraction (HFpEF)R01HL146158 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI BAIREY MERZ, CATHLEEN NOEL · 2019 to 2023
$3.7M
Myocardial Steatosis in Women with Coronary Microvascular Dysfunction: Defining the Pathway to Heart Failure with Preserved Ejection Fraction (HFpEF)R01HL153500 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI WEI, JANET · 2021 to 2025
$3.2M
Accurate, Needle-Free, MRI-based Detection of Ischemic Heart Disease without Contrast AgentsR01HL148788 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI DHARMAKUMAR, ROHAN · 2020 to 2023
$3.0M
Noninvasive Testing of Coronary Microvascular Reactivity Using High-resolution Free-breathing MRIR01HL153430 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI SHARIF, BEHZAD · 2020 to 2024
$2.9M
Motion-Resolved, Comprehensive Quantitative Tissue Characterization Using MR MultitaskingR01EB028146 · NIBIB · CEDARS-SINAI MEDICAL CENTER · PI CHRISTODOULOU, ANTHONY G, LI, DEBIAO · 2019 to 2022
$2.5M
SSFP Cardiovascular MR Imaging on 3.0T Using Unified-Coil Local ShimmingR01HL156818 · NHLBI · WEILL MEDICAL COLL OF CORNELL UNIV · PI SPINCEMAILLE, PASCAL, YANG, HSIN-JUNG · 2021 to 2024
$2.5M
Fully Quantitative Low-Dose, Motion-Resolved Dynamic Contrast-Enhanced MRI in Pancreatic AdenocarcinomaR01EB032801 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Anthony G Christodoulou, Debiao Li · 2022 to 2026
$2.1M
Multi orientation Quantitative Susceptibility Mapping for Accurate Quantification of Iron in Hemorrhagic Myocardial InfarctionR01HL181091 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Rohan Dharmakumar, Hsin-Jung Yang · 2025 to 2026
$1.5M
NHLBI NIH HHS R01 HL127153NHLBI NIH HHS R01 HL133407NHLBI NIH HHS R01 HL146158NHLBI NIH HHS R01 HL148788NHLBI NIH HHS R01 HL153430NHLBI NIH HHS R01 HL153500NHLBI NIH HHS R01 HL156818NHLBI NIH HHS R01 HL165211NHLBI NIH HHS R01 HL181091NIBIB NIH HHS R01 EB028146NIBIB NIH HHS R01 EB032801
6 · The paper itself

Abstract

Purpose To evaluate the performance of a delayed-phase dynamic contrast-enhanced (dDCE) MRI model in quantitative assessment of myocardial tissue physiology and late gadolinium enhancement (LGE) within 5 minutes after contrast material injection in reperfused myocardial infarction (MI). Materials and Methods This animal study included 11 canines (seven female) with reperfused MI. A dDCE model using dynamic postcontrast T1 maps was adopted to depict an unbiased contrast material washout process. The dDCE parameters derived from the 30-minute contrast material washout process (dDCE

Indexed as

Contrast MediaImage EnhancementMagnetic Resonance ImagingMyocardial InfarctionAnimalsDisease Models, AnimalDogsFemaleMyocardiumContrast MediaDynamic Contrast-enhanced MRIIschemic Heart DiseaseMRIMyocardial InfarctionPharmacokinetics

Identifiers

PMID40874838
PMCPMC12892416

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.