Evidence map›Paper›PMID 40874746›Full record

ReviewmBio2025

Rethinking the drivers of coronavirus virulence and pathogenesis; toward an understanding of the dynamic world of mutations, indels, and recombination within the alphacoronaviruses.

Ximena A Olarte-Castillo, Laura E Frazier, Jessica C Gomes Noll, Annette Choi, Gary R Whittaker

Abstract readReview
In one paragraph

Review in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ximena A Olarte-CastilloDepartments of Microbiology & Immunology and Public & Ecosystem Health, Cornell University, Ithaca, New York, USA.ORCID 0000-0001-5310-9622
Laura E FrazierDepartments of Microbiology & Immunology and Public & Ecosystem Health, Cornell University, Ithaca, New York, USA.
Jessica C Gomes NollDepartments of Microbiology & Immunology and Public & Ecosystem Health, Cornell University, Ithaca, New York, USA.
Annette ChoiDepartments of Microbiology & Immunology and Public & Ecosystem Health, Cornell University, Ithaca, New York, USA.
Gary R WhittakerDepartments of Microbiology & Immunology and Public & Ecosystem Health, Cornell University, Ithaca, New York, USA.ORCID 0000-0001-8037-3816

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alphacoronaviruses are widespread but understudied in comparison to betacoronaviruses. Within the alphacoronaviruses is the species

Indexed as

AlphacoronavirusCoronavirus, FelineCoronavirus InfectionsMutationRecombination, GeneticAnimalsCatsDogsFeline Infectious PeritonitisGenome, ViralHumansPhylogenySpike Glycoprotein, CoronavirusSwineVirulenceSpike Glycoprotein, CoronavirusAlphacoronaviruscanine coronavirus (CCoV)feline coronavirus (FCoV)genotypeinsertions-deletions (indel)pathogenesisporcine coronavirusrecombinationvirulence

Identifiers

PMID40874746
PMCPMC12505906

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.