Evidence map›Paper›PMID 40874693›Full record

ArticleFuture medicinal chemistry2025

Analysis of antimicrobial activity and biofilm inhibition of Ag-NHC complexes by in-vitro and molecular docking method.

Neslihan Şahin, Elvan Üstün, Uğur Tutar, Cem Çelik

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neslihan ŞahinFaculty of Education, Department of Mathematics and Science Education, Sivas Cumhuriyet University, Sivas, Türkiye.
Elvan ÜstünFaculty of Art and Science, Department of Chemistry, Ordu University, Ordu, Türkiye.
Uğur TutarFaculty of Pharmacy, Department of Pharmaceutical Botany, Sivas Cumhuriyet University, Sivas, Türkiye.
Cem ÇelikFaculty of Medicine, Department of Medical Microbiology, Sivas Cumhuriyet University, Sivas, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsMetal-N-heterocyclic carben (NHC) complexes have garnered significant attention from synthesis chemistry. Silver is well known for its broad-spectrum antimicrobial activity, and it exhibits their activities with different mechanisms. In this study, we combined these two important scaffolds, analyzed for possible antimicrobial and antibiofilm activity, and evaluated the interactions against DNA Gyrase, SarA, Human Serum Albumin, and DNA for getting insight into the antimicrobial and antibiofilm details. MATERIALS &

methodsFour new Ag-NHC complexes ( RESULTS AND

conclusions

Indexed as

Anti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsBiofilmsCoordination ComplexesMolecular Docking SimulationSilverCandida albicansDNADNA GyraseHumansMicrobial Sensitivity TestsMolecular StructureSerum Albumin, HumanStructure-Activity RelationshipAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsCoordination ComplexesDNADNA GyraseSerum Albumin, HumanSilverantimicrobialbiofilm inhibitionmolecular dockingN-heterocyclic carbeneSilver complexes

Identifiers

PMID40874693
PMCPMC12582079

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.