Evidence map›Paper›PMID 40874671›Full record

ArticleGeriatrics & gerontology international2025

Emergency department attendance stratified by cause and frailty status: A national retrospective cohort study.

Balamrit Singh Sokhal, Andrija Matetić, Joanne Protheroe, Toby Helliwell, Phyo K Myint, Timir K Paul, Christian D Mallen, Mamas A Mamas

Abstract read
In one paragraph

Article in Geriatrics & gerontology international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Balamrit Singh SokhalSchool of Medicine, Keele University, Keele, UK.ORCID https://orcid.org/0000-0002-2315-0744
Andrija MatetićKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, UK.
Joanne ProtheroeSchool of Medicine, Keele University, Keele, UK.
Toby HelliwellSchool of Medicine, Keele University, Keele, UK.
Phyo K MyintAberdeen Cardiovascular and Diabetes Centre, School of Medicine, Medical Sciences and Nutrition, University of Aberdeen, Aberdeen, UK.ORCID https://orcid.org/0000-0003-3852-6158
Timir K PaulAscension St. Thomas Hospital, University of Tennessee Health Sciences Center at Nashville, Nashville, Tennessee, USA.
Christian D MallenSchool of Medicine, Keele University, Keele, UK.
Mamas A MamasKeele Cardiovascular Research Group, Centre for Prognosis Research, Keele University, Keele, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to determine whether the causes of emergency department (ED) attendance and clinical outcomes vary by frailty status.

methodsUsing the Nationwide ED Sample, causes of attendance were stratified by Hospital Frailty Risk Score (HFRS). Logistic regression was used to determine adjusted odds ratios (aORs) and 95% confidence intervals (95% CIs) of ED and overall mortality.

resultsA total of 155 497 048 ED attendances were included, of which 125 809 960 (80.9%) had a low HFRS (<5), 27 205 257 (17.5%) had an intermediate HFRS (5-15), and 2 481 831 (1.6%) had a high HFRS (>15). The most common cause of ED attendance in the high-HFRS group was infectious diseases (43.0%), followed by cardiovascular diseases (CVD) (24.0%) and respiratory diseases (10.2%). For the low-HFRS group, musculoskeletal disease was the most common cause (21.2%), followed by respiratory diseases (20.6%) and gastrointestinal diseases (18.5%). On adjusted analysis, high-HFRS attendances had increased overall mortality (combined ED and in-hospital) across most attendance causes, compared with their low-risk counterparts (P < 0.001). High-HFRS attendances with infectious diseases, CVD, and respiratory diseases had an increased risk of overall mortality, compared with their low-risk counterparts (aOR 23.88, 95% CI 23.42-24.34 for the infectious disease cohort; aOR 2.58, 95% CI 2.55-2.61 for the CVD cohort; and aOR 36.90, 95% CI 36.18-37.62 for the respiratory disease cohort).

conclusionsFrailty is present in a significant proportion of ED attendances, with the cause varying by frailty status. Frailty is associated with decreased ED and increased overall mortality across most attendance causes. Geriatr Gerontol Int 2025; 25: 1350-1358.

Indexed as

Emergency Service, HospitalFrail ElderlyFrailtyAgedAged, 80 and overCardiovascular DiseasesFemaleGeriatric AssessmentHospital MortalityHumansMaleMiddle AgedRetrospective StudiesRisk AssessmentRisk FactorsUnited Statesemergency departmentfrailtymortalityoutcomesrisk factors

Identifiers

PMID40874671
PMCPMC12501700

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.